It's not just obesity. Drugs like Ozempic will change the world

https://www.economist.com/leaders/2024/10/24/its-not-just-obesity-drugs-like-ozempic-will-change-the-world

by Anon84 • 2 years ago

32 167 2 years ago

We don’t know long-term effects yet. Interfering with hormones and their receptors can change the amount of the hormone the body produces and the sensitivity of the receptor. If it’s applied carefully then it shouldn’t be a problem though and the body would re-regulate later itself for the trade of many positive effects immediately.

hatenberg• 2 years ago

People keep saying that but we've had GLP-1's in active use on millions of people for decades in diabetes care.

cyberax4• 2 years ago

Liraglutide has been in clinical use for two decades, with no real serious downsides.

orionsbelt• 2 years ago

Gastropreisis may be a rare side effect, but is serious and appears to a be a real risk.

ajhurliman2• 2 years ago

GLP1s have been on the market for at least a decade, they’re pretty well studied at this point. Their sudden popularity is due to the FDA allowing it to be prescribed for obesity (instead of diabetes), not the discovery of a new drug.

Karunamon• 2 years ago

Wait a sec. Something which provides such an unambiguous quality of life upgrade by addressing one of the biggest health problems in the country, is only now available because of regulations?

Surely it's not that simple.

cyberax4• 2 years ago

Their sudden popularity is due to the FDA allowing it to be prescribed for obesity (instead of diabetes), not the discovery of a new drug.

That's not true. I started on liraglutide, which is a previous-gen GLP-1 agonist. It was approved for that purpose in early 2010-s. It worked, but it required daily injections due to its short half-life. It also was unpleasant, as you could feel its effects wax and wane throughout the day.

Ozempic was approved for diabetes in 2018, but became available in sufficient quantities for that purpose in 2019. Doctors started prescribing it off-label for weight loss in 2020 (that's when I also got switched to it), and it was approved by the FDA for weight-loss in mid-2021.

So while we could have moved faster, it's not like there were decades of time lost.

stevenAthompson11• 2 years ago

We kind of do know the long term side effects. Exenatide has been in use since around since 2005. They can include pancreatitis and thyroid cancer in a small percentage of the population. Modern GLP-1 agonists exhibit essentially the same threat profile.

EDIT - Just wanted to note that the cancer thing has only been seen in rats. Not humans. After 20 years we'd probably have seen it by now.

A_D_E_P_T3• 2 years ago

Thyroid cancer sounds more scary than it actually is. It's one of the weakest forms of cancer, and it's extremely easy to treat if caught early enough. Also, living without a thyroid is no big deal.

Somebody very near and dear to me was diagnosed with thyroid cancer ten years ago, and now has no thyroid. She's hardly inconvenienced by it & hasn't even gained any weight since then. Just gotta remember to take those T4 tablets in the morning, is all.

Point is: If you weigh in the balance [lives saved or QALY gained due to GLP agonist administration] vs. [lives lost or QALY lost due to thyroid cancer secondary to GLP agonist administration], it's not even going to be remotely close. "Lives saved" will probably win by an enormous margin, maybe a factor of twenty or so.

jessriedel• 2 years ago

Shouldn’t we have a non-negligible prior on possible cancer risks at all timescales? That doesn’t mean we don’t approve drugs without 80-year clinical trials, but I think it’s a non-negligible risk that has to be accepted.

For instance, my impression is that lung cancer rates only really become strongly pronounced — in the sense of being statistically detectable in the small population sizes you find in clinical studies, rather than the entire US population — after like 15 years of smoking. (Correct me if I’m wrong.)

ZYbCRq22HbJ2y74• 2 years ago

EDIT - Just wanted to note that the cancer thing has only been seen in rats. Not humans. After 20 years we'd probably have seen it by now.

It is common to see this repeated, but there is some literature that correlates thyroid cancer in humans with usage of GLP-1 agonists.

One example (2023): https://pubmed.ncbi.nlm.nih.gov/36356111/

swatcoder2• 2 years ago

It's okay.

We go through this every 10 years or so, for at least the last 100 years. The market doesn't really have the patience to wait to see the aggregate or long-term effects of new "pop culture" drugs and formulations so we just charge ahead and then let another generation deal with whatever mess. When the pharmaceutical companies really luck out, the cleanup can even come through yet another such wonder drug.

Extropy_13• 2 years ago

This is exactly right. Let the market decide. If people want to use new experimental drugs, why not let them have at it. They oughta be responsible for their choices

PNewling2• 2 years ago

Not trying to argue, more just curious, what drugs are you referring to with this comment?

VoodooJuJu• 2 years ago

Oh you just done a heckin double badspeak. Not only are you not trusting my science, but you're slandering my big pharma. Big mistake. Thats a downvote.

welferkj• 2 years ago

But we know the long-term effects of obesity, alcoholism, and every other form of spiritual weakness this thing apparently allows people to escape. The long-term effects would have to be comically atrocious for it not to be worth it. Put ozempic in the water supply.

PNewling2• 2 years ago

So I agree with all of this, but will add we do know the long-term effects of obesity, diabetes and a host of the other things it is showing some potential signs of helping with. And because of the serious damage being done by those issues ([0] heart disease is the leading cause of death in the US), it just needs to be good enough to help resolve those issues without introduction anything too major as far as long term side-effects.

This is all to say, because of the current state of health norms (at least in the US), it just has to not do too much damage long term and the pro's can still outweigh the con's of its use.

[0] https://injuryfacts.nsc.org/all-injuries/deaths-by-demograph...

wyre2• 2 years ago

We don’t know long-term effects yet.

Compared to the long-term effects of obesity, Alzheimers, and addiction? Everything treatable by Ozempic, et al. has immediate short-term effects, and long term effect that significantly effect longevity.

The fearmongering around Ozempic not knowing the long-term effects would have to be is unnessicary. Yes, it sucks to have to be stuck taking a medication for the rest of your life, but would you rather be stuck with a delibitating disease and die 10 years early, or have to take a medication for the rest of your life?

hagbard_c2• 2 years ago

would you rather be stuck with a delibitating disease and die 10 years early, or have to take a medication for the rest of your life?

I'd rather have a cure for that disease instead of lifelong medication. While not nearly as profitable it is far preferable over a lifelong dependency.

notpushkin2• 2 years ago

https://archive.is/tLaw3

randcraw• 2 years ago

Thanks, but site broken. It prompts with an infinite series of images.

MegaDeKay• 2 years ago

Worked for me. On Firefox if that matters...

Jtsummers• 2 years ago

This is usually because you're using Cloudflare DNS. archive.is doesn't play well with it, deliberately.

Extropy_13• 2 years ago

To me at least, celebrating individuals using drugs that support an unhealthy lifestyle does not appear like a positive for society at large. I thought medicine was about aiding people to become healthy, not providing quick fixes to common problems. Why is this being celebrated?

EDIT: I do not mean to say Ozempic is useless or dangerous, only that celebrating it as a solution to the problem of obesity is. It is certainly a tool that helps people. I don't think it should be relied on continously. People need to live healthy lives to be healthy. I am not perfect, no one is. Losing weight is hard.

eska2• 2 years ago

What I’m afraid of is that this just ends in an arms race of ever unhealthier lifestyles versus medication to counter-balance that. These aren’t wonder drugs. People just need to stop eating garbage food, and too much of it. And the government should pass laws to facilitate that to counter lobbyists

BitwiseFool• 2 years ago

"People just need to stop eating garbage food, and too much of it."

Easier said than done. However for the vast majority of the people taking these drugs, these drugs enable them to finally do that.

selectodude• 2 years ago

This is a drug that literally turns off the part of your brain that craves overeating. Governments can’t legislate against human nature, as much as the nanny state wants to. We fixed food production without fixing the scarcity mindset that got us here. Now we’ve fixed that too.

daedrdev8• 2 years ago

But this drug is basically mind controlling people to live healthier. Its not countering an unhealthy lifestyle, it improving their current lifestyle

sodality23• 2 years ago

They don't support an unhealthy lifestyle any more than a miracle pill that stopped a harmful drug addiction would. Would you oppose its release since it's not actually "natural" to use medicine to stop your addiction, when you should instead use pure willpower? This simply doesn't make sense.

We live in a world of enormous abundance, exacerbated by companies min-maxing foods to have the most addictive properties humanly possible, at cheap prices.

throwaway199725• 2 years ago

I realize obesity is a major problem, but so is neuroticism about health, weight, and diet. I agree with the nagging feeling that using a drug to address hunger is likely to have negative consequences for some people.

EDIT: obsession -> neuroticism

Extropy_13• 2 years ago

I don't oppose the use of this drug or its release. People should be allowed to do what they will. I see harm in celebrating the drug as a cure to obesity. Of course, certain diseases may make it easier for you to gain weight. Though obesity is not like cancer, it is a condition brought on by unhealthy behaviours

taeric• 2 years ago

Its being celebrated because it is an amazing development? I think I can agree that, ideally, people will bootstrap healthy lifestyles and not need the aide long term. I don't know how you could justify that as a reason not to be glad the aide exists, though?

daedrdev8• 2 years ago

This medicine literally aids people to become healthy. They will gain years of life from the lost weight.

Their lifestyle changes to be healthier by eating less, which many are unable to do without help because the human body has millions of years of baked in evolution demanding we overeat if able

Extropy_13• 2 years ago

My father has used ozempic. He hails it as a wonder drug, yet he does little to nothing to change his behaviours because he can rely on this crutch. I see that as concerning

GooglyThird• 2 years ago

Think I generally agree with your sentiment, but my understanding of how Ozempic works is that it kills your appetite. The "unhealthy lifestyle" you're referring to is one of overeating. Ozempic doesn't support a person to continue overeating, it removes the desire to overeat. From that perspective it is aiding people to become healthy.

Extropy_13• 2 years ago

Sure, yes it is aiding people to become healthy in that sense. Is it healthy to rely on drugs to change your thought and behaviour patterns? I definitely see this drug as a useful tool when combined with a plan to not continue using it for the rest of your life. I see relying on this drug continuously as a problem, thinking "oh, there's no need to try and change my behaviours on my own, this drug will do it for me."

graeme3• 2 years ago

Not how it works. Ozempic seems to shift processes in the body that divert you from the unhealthy lifestyle

stevenAthompson11• 2 years ago

I guess it's because some of us aren't as perfect as you.

If humans stopped eating sugar we wouldn't need most dentists. Should we stop celebrating dental advances?

Extropy_13• 2 years ago

Dentists will tell you to eat less sugar. The company that manufactures ozempic will tell you that you don't have to do anything but use our drug

Oarch• 2 years ago

Why is this being celebrated?

Call me cynical, but maybe because Big Pharma has the deepest pockets and is one of the largest (if not the largest) spender on advertising out there.

daedrdev8• 2 years ago

Or maybe its because the majority of the population will loose years of life from being overweight or obese

satisfice• 2 years ago

It’s only unhealthy if the drug isn’t used.

Imagine if there were a button on your head that when you pushed it all alcohol in you blood would be cleared out with no negative effect on your liver. In that case, heavy drinking would NO LONGER BE an unhealthy lifestyle. Kids would be able to drink alcohol with no problems.

javier1234543214• 2 years ago

Its weird that people are celebrating the fact that our lifestyle and food supply is so bastardized that it's causing people to become unhealthy to the point where they need a lifelong drug to overcome it. I get why the manufacturers and big pharma likes it, but it seems that it's also celebrated by many individuals, like you see in this and other HN threads.

This drug is a symptom of a sick culture, and not cause to celebrate. I don't at all blame the individuals that have this prescribed to them for taking it, but it just seems like a technochratic solution addressing superficial symptoms of a much larger problem.

stevenAthompson11• 2 years ago

Smoking causes lung cancer. I don't smoke, but if they found a cure for lung cancer I would celebrate that rather than griping about "personal responsibility" or whatever it is your grievance here is.

This thing objectively and subjectively improves the lives of the people you share this world with. If you have a problem with that it might be time to turn your gaze inward.

r00fus2• 2 years ago

I thought medicine was about aiding people to become healthy

This is exactly what this medication does. I don't understand what confusion there is - this medication undoes the damage that a poor lifestyle choice creates, then gives the user to choose again.

nthdesign• 2 years ago

I've struggled with weight my entire life (I'm in my forties). Back in 2019, I lost 80 pounds. I carefully regulated my calorie intake to 1,800 per day. I discovered I have an absolutely terrible sense of portion size, and absolutely never feel "full" or satiated. I also made it a point to close all three Activity rings on my Apple Watch every day. I felt better, I had more energy, and I was able to enjoy more things in my day-to-day life. Even with all of those positives, a series of difficult life events during the first year of COVID took me out of my routine, and I haven't been able to bounce back. I would like to try a GLP-1 to see if it could give me a boost in the right direction again. I have no interest in being on it, or any medication, forever.

Thankfully, I've never been addicted to anything other than food. I never liked alcohol, nor did I get any positive feeling from it. So, I don't drink. I've never been enticed by drugs, so I've never used them. I went to Atlantic City once, but have never gambled another day in my life. Being spared from these other addictions isn't a matter of my amazing willpower. I'm simply not drawn to those addictions. Nor do I think that people who battle those addictions simply have a lack of willpower. I believe it's much deeper than that.

I agree that celebrating a medication as a cure-all solution is problematic. But, I don't think that's what most people think about GLP-1s. I think most most people simply want, and deserve, a little help in a difficult and complex world.

consteval12• 2 years ago

support an unhealthy lifestyle

Do people not know what Ozempic does?

Ozempic doesn't make you sit around, eat like a pig and you lose weight. That's not what it does.

Ozempic makes you eat less, curbing overconsumption. People on Ozempic are also much more likely to exercise. It does not "support an unhealthy lifestyle". It literally does the opposite.

People need to live healthy lives to be healthy

Okay, Ozempic helps people live healthy lives. Just like having a personal trainer helps people live healthy lives.

Would you say having a personal trainer is "supporting an unhealthy lifestyle"? Of course you wouldn't.

EcommerceFlow• 2 years ago

If we can alter the chemical composition of peoples brains/guts to make them less hungry, how long until something similar exists to overcome anxiety? Public speaking fears? etc.

stevesimmons• 2 years ago

It's called alcohol

graeme3• 2 years ago

The answer is Ozempic seems to do this already.

My theory is that something goes haywire in the body and causes many issues. Obesity being the most visible of these but far from the only issue.

GLP-1 agonists reverse this thing that went haywire and fix many issues

https://www.medicalnewstoday.com/articles/weight-loss-drugs-...

willsmith72• 2 years ago

Or... Non-obese people average better mental health than obese people.

That article is all just correlation. Which cause is more likely?

HPsquared• 2 years ago

Generative AI, possibly combined with VR, could be great for people with social phobias. Or terrible, I've not decided which. It'll definitely have some effect!

xk_id4• 2 years ago

Damn. What about crypto? The holy trinity that will fix everything. Please, they must be able to fix something, anything!

Duwensatzaj• 2 years ago

Beta blockers for anxiety have existed for a long time. Or for a stronger effect, Xanax and other benzodiazepines.

bzhang255• 2 years ago

For people who suffer from anxiety, there already exists a plethora of anti-anxiety medication, both short-term and long-term.

m463• 2 years ago

I thought I read that tylenol can help with social anxiety like public speaking.

EDIT: https://news.ycombinator.com/item?id=31263305

Nashooo• 2 years ago

It's so weird to me that with a vaccine against COVID the populace was going all conspiracy theorist. Saying the longterm effects are unknown etc. But with these kind of drugs there are suddenly no issues.

cnlwsu• 2 years ago

This has 10+ years with tons or people and studies over the side effects. Not to justify the the conspiracy theories, but it’s not apple to apples

mynameishere• 2 years ago

If people were compelled to take Ozempic to keep their jobs, there would be "issues".

tom_• 2 years ago

You could be seeing two different sets of people, largely non overlapping.

xk_id4• 2 years ago

Ozempic and other research peptides are very popular in online biohacking communities. The same communities were against vaccines. This paradox has been pointed out quite often and it became a meme.

kubectl_h5• 2 years ago

What makes you think these two are comparable? Just that they are drugs? No one is requiring anyone to take these drugs -- people are coming to the conclusion on their own. And a lot of people taking these drugs are not paying the companies that own the production of them. The rapid rise in compounding pharmacies (think of these as "wildcat" pharmacies) producing these drugs is currently causing an opportunity cost to the owners of patents of these drugs. There really isn't any conspiracy here.

And there is no shortage of moralizing and FUD about these drugs. Just read this comment thread.

rmellow• 2 years ago

Ceci n'est pas un submarine.

siliconc0w• 2 years ago

I wonder if all these other 'bonus' effects really just stem from the same root cause which is effectively food that is just really bad for us. So if you eat less poison, you get a lot healthier - not just slimmer.

justmarc2• 2 years ago

This, and most likely a lot of this "research" will be debunked in due time (years, decades), and new, currently unknown side effects will come to light.

How can some engineered drug be a solution to a life choice problem? Typical human behavior to look for easy "solutions" that don't actually solve anything, just delay or temporarily mitigate a problem.

sodality23• 2 years ago

Is your opposition to these drugs that you think the patients haven't somehow earned the right to be rid of their ailments, or that they have side-effects (thyroid problems, yo-yo problems for weight lost, etc)? The first one is a moral judgment, the second one is a claim that should be backed by evidence.

tshaddox3• 2 years ago

Why would engineering (of anything!) be a valid approach to some problems but not others?

If I want to move cars across a body of water then engineering is a great approach. Why would it not also be a great approach if I want to change my eating habits?

consteval12• 2 years ago

life choice problem

Not this simple.

Choice isn't binary, it's incredibly complex. There're millions of individual little effects that go into each and every one of your choices. You actually have no idea how much influences you have over your "choices". In fact, almost everything you do in life is completely out of your control - you just do it, it's habit. Is brushing my teeth a choice? Certainly, I do it, but I also don't make that choice ever, it just happens.

Why is it that some can drink every week and be fine, but some can't ever drink because they are alcoholics? Why is it that I am able to eat as much as I want, and I'm not fat?

You could just be lucky enough that you do not have a propensity to overeat. Neither do I. But be humble, have some humility. You and I are privileged. I did nothing to earn this. I eat what I want, when I want. It's merely a coincidence the what and when happens to not harm me.

bevesce-• 2 years ago

I'm rather thin and fit. I eat mostly healthy food with some unhealthy indulgences from time to time (cold cuts, fatty cheese, bread, croissant from a bakery). I eat controlled portions so I don't lose or gain weight. I'm hungry all the time and quite miserable. I spend most of my wake time thinking about the next meal. What life choice should I make?

bryanlarsen2• 2 years ago

"the dose makes the poison" - Paracelsus

kubectl_h5• 2 years ago

Near immediate moderation of alcohol consumption in many people who are taking this drug has nothing to do with what or how much they eat. It is altering the brain function in some way.

tshaddox3• 2 years ago

I think I would count alcohol consumption as “eating” in this context.

bryanlarsen2• 2 years ago

When I'm dieting I crave beer. When I'm not dieting I prefer Gin or Scotch in moderate quantities. My body appears to know that alcohol contains calories.

kubectl_h5• 2 years ago

I can't read the article but I have kept up with the almost daily revelations about this class of drugs so I have an idea of what its about. I am truly hopeful for the kinds of society wide changes it promises to bring about.

We seem to be rapidly approaching an inflection point, brought on by the compounding distributors such as Hims, that will need to be resolved: there are probably more people on the compounded version of this drug than most suspect and that number is growing by the tens of thousands every day. Meanwhile, Norvo Nordisk is trying to shut down this channel of distribution. That would be a bad idea and I think the FDA must be aware of that. This conflict between NN and the compounders needs to be resolved.

Personally I think the promise of this drug makes it a moral issue and have little sympathy for NNs position here: they will need to capitulate on their control over it and accept some kind of suboptimal pricing agreement. The potential positive outcomes of this drug supersedes their sole claim to it IMO.

r00fus2• 2 years ago

I mean there are many GLP-1 weight loss drugs, and only one of them is from NN.

kubectl_h5• 2 years ago

You are right. What I meant is sole claim to production of semaglutide. If they want to produce the injector version, which is considerably more expensive and more difficult to produce (and thus justifies their exorbitant pricing) as opposed to what the compounders are doing, then they are not acting in good faith here and are purposefully slow walking a product that is in incredible demand.

songbird23• 2 years ago

I tried Ozempic for three months, gradually increasing the dose monthly. Then, on the fourth month, I switched to Mounjaro and continued it for five months. It did help me lose weight, but the discomfort in my upper left abdomen turned into pain. It felt like the food I ate was still in my stomach, undigested, even four days later. I eventually stopped because I was worried it might have harmed my pancreas. A year later, I still occasionally experience the same abdominal pain. but doctor didn't didn't see pancreas issue. I It did help with my blood sugar management(diabetes) and weight though, but ill never do it again and stick to IF

wouterjanl• 2 years ago

Living without appetite. I get it can help some people with losing weight. But doesn’t it sound a tad sad too? Isn’t desire one of the most complex, beautiful emotions?

ZYbCRq22HbJ2y74• 2 years ago

Your picture of desire and the reality of addiction are very different things

daedrdev8• 2 years ago

Many people do not want to eat how they do, the just cannot help themselves

tshaddox3• 2 years ago

Unwanted desires are extremely uncomfortable.

ryandrake• 2 years ago

I don't suffer from an uncontrollable appetite, but for those who do, I would imagine that compulsive-anything is undesirable and eliminating it is an unambiguously positive miracle.

If a drug can cure an out-of-control appetite, can it cure chemical addictions? Compulsive gambling? None of these are beautiful emotions.

fragmede3• 2 years ago

Funny you should say that. There's mounting anecdotal evidence that GL-1's curb addiction more generally, including the two you mentioned, SUD/chemical and gambling. There are currently trials underway to try and prove that scientifically.

https://news.unchealthcare.org/2023/12/use-of-glp-1-receptor...

consteval12• 2 years ago

Yes but when your brain is broken and the desire a liiiiitle too strong it becomes bad.

I smoked. The desire to have a cig was debilitating. And I didn't want it, I never wanted it. But the sheer desire would bring me to my knees.

xk_id4• 2 years ago

Desire is a function of the separation from divinity.

joquarky2• 2 years ago

Isn’t desire one of the most complex, beautiful emotions?

Perhaps, but it's also the source of suffering.

Shadowed_• 2 years ago

Not without but with reduced appetite.

Fire-Dragon-DoL2• 2 years ago

I eat probably 12 times per day, mostly fruit with 3 main meals. I'm always hungry, I'd love to eat even 6 times instead.

I like food, don't get me wrong, but being constantly hungry is very annoying

f38zf5vdt• 2 years ago

The current narrative of Ozembic reminds me a lot of the 1930s narrative around amphetamine. [1] The mood booster wonder drug was used extensively in the military and civilian population, from soldier to politician. Indications included weight loss, depressed mood, alcoholism [2], and fatigue.

Another early pharmacologic approach to alcoholism treatment used psychostimulants to create a feeling of well-being and obviate the euphoric effects of alcohol. Bloomberg (1939) administered amphetamine to 21 alcoholic patients, who became more alert and energetic and reported no desire to drink (see also Bowman and Jellinek, 1941). Reifenstein and Davidoff (1940) found that amphetamine was of benefit in cases of acute alcohol intoxication and recommended it to treat depression in institutionalized alcoholics (see also Bowman and Jellinek, 1941).

Of course, I'm interested, but I will let medical science do the damage first before I elect to dive in.

[1] https://ajph.aphapublications.org/doi/pdf/10.2105/AJPH.2007....

[2] https://pmc.ncbi.nlm.nih.gov/articles/PMC4453501/

bdz• 2 years ago

I'm on Saxenda for 3 months now (basically Gen 1 of the same GLP-1 drug, Ozempic being the Gen 2, both made by Novo Nordisk).

The hunger suppression is real and what's intersting that this is the first time I've felt that I'm "not in control of my thoughts". Of course it's my own decision to take the drug is not about that. But I'm not hungry anymore, I don't binge eat anymore, and I generally don't enjoy food as before. Like even if I have my favorite foods it's just an OK experience. It's like I'm eating because I know I need energy to live but otherwise it's totally gone as the "main focus" from my daily life (which was my main eating disorder)

bitshiftfaced• 2 years ago

what's intersting that this is the first time I've felt that I'm "not in control of my thoughts".

What do you mean?

firecall• 2 years ago

I also recently started taking Saxenda, and I’ll give my take on what they mean:

I found it remarkable that almost immediately after taking the drug it began to work.

And by work I mean that it removed any thoughts I had about eating.

What you feel like eating isn’t a thought or conversation with yourself that you have any more.

It’s a rather strange feeling, but also one you don’t notice as it’s an absence of something that you don’t even miss once it’s gone!

LOL - seeing as this is HN, I’ll make a joke and go as far to say that these drugs are a productivity unlock hack!

Why waste time eating when you could be building the next unicorn!

joquarky2• 2 years ago

It's one of the first things that people typically discover when meditating.

valval2• 2 years ago

You perfectly summarise my relationship with food, although I’ve never taken any appetite suppressants. I spent my early adulthood competing in bodybuilding, and ever since I can’t really treat food as entertainment.

I cherish every meal I have and everything tastes amazing to me, since I only eat to hunger. Food can’t get better to me than the stuff I eat every day, so I don’t go out or spend money on fancy food. I just eat what keeps me healthy.

I’m not sure if it’s a good or bad thing that people are now able to join this camp without destroying their relationship with food through questionable activities.

z3ncyberpunk• 2 years ago

Yeah, change the world for the worse.

It's not just obesity. Drugs like Ozempic will change the world

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