Ask HN: What is your preferred method of sending large files over the internet?

If you have, say, a several GB file (too large for something like email or standard Dropbox, but not big enough to warrant at specialized solution) and need to send it to an individual or a small group of people, without being able to physically hand them a thumb drive, how would you personally go about doing so?

This seems like it would be a solved problem for the day and age, but I've yet to really find a good solution.