semperdark

However GameStop does have like $9 billion in cash on hand if I recall correctly.

MATH 217 was one of my favorites! Ive heard that the math department can be a little unenthusiastic about the non-major courses, but overall it’s a really welcoming place in my experience.

Not sure it's quite so clean. My first was a a girl in underwear standing in front of a wall and turning while introducing herself "My name is __ and I am 19 years old..."

You're not wrong. But over the enormous amount of time since, the "duplicate" organelles and systems needed for independent living were steadily carved out of mitochondria. While they do have their own DNA and replication process, the DNA is basically limited to specific things they need to perform their energy-generation functions and the replication happens when triggered by host cell replication.

It's a bit like if you took the heart from an animal and transplanted it into a human: is it meaningful to call it independently alive? Maybe, it depends what question you're trying to ask.

Unmodified C elegans can certainly live to 3x reproductive age, fwiw. These are all simplistic model organisms by definition but many nearly identical proteins are found in humans and there’s value to studying their structure and function in a very well-known environment. I wouldn’t take it as “just delete IL11 and you’ll live to 130!” but the fact that it’s presented that way is more the fault of marketing departments and science writers.

True, though largely limited to DNA necessary for its functions. I don’t have a citation on me (mobile) but there’s evidence that more “generic” mitochondrial DNA was integrated into the nuclear DNA, and that this is also the case for other endosymbionts.

"Driverless cars are easy, just follow the rules of the road!"

In addition to the other comment, it's also missing a lot of card types that Anki supports. However, I think this is made up for by the knowledgebase features, so you can use it to take notes stored with / linked to by your SRS.

I can wholly recommend Mochi: it’s great looking but also quickly becoming feature competitive with Anki. It’ll be a long time before anything hits the long tail of Anki features, but I find the trade offs to be more than worth it.

Not just talking to the press, attempting to hire an attorney to represent the chatbot. Seems a little… eccentric.

Amazing who you run into on this site. In High School (~2010 on) I played through your games as fast as you could make them. Thanks for the hours!

HIPAA, maybe. HITECH and Meaningful Use would be more relevant (2009 onwards).

It's been a while, but I remember thousands of pages of granular user-interface-level requirements (think 'display of telephone number icons') to quality for federal recognition as an electronic medical record system. Hospitals/clinics not using a federally-approved vendor received increasing % penalties to their reimbursements as deadlines passed. Forcing through EMR adoption was meant to improve outcomes.. or something.

Some of the requirements are defined by references to standards prepared by consulting companies, which charge for access to these standards. Additionally, certification of compliance with standards was farmed out to a couple consulting companies.

Is this something you're doing yourself for mental health or something being imposed upon you that you're trying to deal with?

Computer-savvy people dismiss dark patterns like this as mostly-harmless prodding, but it really disorients the less able.

For all industry pats itself on the back for accessibility, they still have absolutely no shame about this open and obvious UX manipulativeness.

I hope your grandfather comes to understand he's not at fault for this absolute bullshit. My father is almost afraid to ask me to fix his systems because he's too proud to keep coming to me with issues - he used to be the technical one!

It's "annoying" when Microsoft continually cons your dementia-suffering family members into switching their browser back to Edge, which has none of their logins or bookmarks. Confusing them, worrying them, and doing real human harm.

Here's to dark patterns built into the OS! UI decisions matter.

Very true; downtown feels like disneyland for the suburbs. I really hope it can make the transition into a more coherent city.

I agree with you that some neighborhoods are being left behind by growth, but what is the alternative?

Leaving aside race, Detroit needs to densify or die - nothing sustainable about supporting services in neighborhoods with one occupied house per block. Duggan has no choice but to chase downtown growth for tax revenue. It's a city with infrastructure built for millions and a population of half a mil.

If Google doesn't trust your browser for whatever reason (eg. privacy-conscious browsing).

Exactly what I mean - the cards end up just being a tech tree in practice. The PDX games really do just need more _content_.

Haha - If you ever end up writing that game, send me a beta invite!

Absolutely, it's been a long while since I booted up Stellaris. Something like Starnet and absurdly hard cling-to-life difficulties brings a little spice, but it's pretty much a solved game of tuning resource flows.

On launch they made a big deal about how they had the "cards" instead of a tech tree... turns out that's pretty much just a tech tree.

You should adjust the "mid-game start year" and "late-game start year" sliders at game setup. Note that those are just the earliest possible start times, and the chance starts rolling yearly.

Definitely frustrating that you have to try to predict the game trajectory in advance. A game going well is almost a bad thing - you end up ahead of the curve and sit around doing nothing.

Some of the comments report training themselves to produce closed-eye visuals, which I could believe with enough practice. I don't think that has anything to do with aphantasia, though, and I'm in the same box you are.

That said the script doesn't seem to work for this course, for me - it downloads sections 0 and 4 then terminates. Anyone else having this issue?

Are there any articles you could link that go into more detail on soil restoration at scale, or specific examples of it?

They allow you to order in advance for discounts, and book all the sales on one day as a PR exercise.

I really enjoy Wren (https://github.com/wren-lang/wren) and have used it for a few of my personal programs.

Most paywalled news sites have exceptions if you're coming from Google/FB. You can hit the "web" link under the title of the article on HN to Google search for it, and then click the article from there.

It is a bit difficult to describe what system is used to coordinate between business units

Well, now I'm interested. Could you try elaborating?

China uses infrastructure spending to stimulate the economy, at the expense of enormous amounts of debt. A lot of this spending goes to essentially unproductive construction, like building subway systems larger than NYC's in small cities.

It remains to be seen whether this will pay off, but they were significantly cutting back on spending before the tariffs started.

Interesting. I've heard that before, it does seem to be mostly a matter of building up a solid reputation over time and getting referrals. Thanks for the info!