robbiep

I was trying to understand how to do this, and I formed the opinion that most of the battery providers don’t really allow the degree of ‘on/off’ or ‘charge/discharge’ customisation as might be necessary to make this work? Or was I fooled by the packaged products that are aiming to turn me and my battery and panels into a residential power plant at the whim of the energy company?

You know what already detects breast cancer? Mammograms followed by ultrasound.

We have screening programs for a reason. We know the sensitivity and specificity of these. They are widely available in any rich country that doesn’t treat its citizens like shit. There will absolutely be better stuff out there as we progress, with better sensitivity/specificity and lower harm (everything medical has some harm quotient) but I have a hard time wrapping my head around how they will best physics to provide better than state of the art today with this technology (and bow they will beat availability of current screening systems)

‘Catfishing is fine’

My impression isn’t that they are trying to improve CTE imaging (did it say that in the article?!) but somehow approach the resolution of being able to run the blood flow data through a black box so they can demonstrate what the occipital cortex is processing. I mean, that’s literally the first part of the article?

Can MRI/CT demonstrate CTE.

Well, like a lot of things which as alzheimers, that is still a pathological diagnosis for the most part, to the best of my knowledge (not post mortem scanning but out some brain tissue on a slide), but this belies the general fact that getting the tissue diagnosis is really not that important to anyone except a pedant, because yes MRI will show changes in grey/white matter differentiation and size compared to age and sex weighted cohort; and CT will show similar; and in fact it is the history and examination that practically matter to both the patients and their family.

So while it’s nice to have a totally 100% bulletproof ‘diagnosis’ for labelling purposes, practically on history and exam it’s not going to change how they are managed or what they and their family do say to day; given that both CTE and basically any of the dementias don’t have any treatment associated with them, and the current neuro imaging we have can deliver much higher resolution than what this is promising anyway (I mean even CT angio, and it’s not using ‘advanced imaging processes’ to create data out of noise)

The methods described in the main article refer specifically to neurovascular imaging. In order to have a higher resolution, they’re making use of microbubbles (which need to be prepared and injected just prior to imaging).

There is no world where vascular imaging with a methodology like this is better than what I can do today in a GP clinic with a handheld GE or butterfly (or similar) US probe for anything that matters:

- for dvts and thrombus I can already image them

- if it’s in the brain the last thing that is useful for you to do is fuck around in a small clinic when you should be getting to a major tertiary centre as soon as possible

Some Microsoft setups ONLY allow Authenticator - can’t use 1pass etc. I have recently fallen into this pit

I am a huge Tchaikovsky fan, mostly as I love his hard sci fi and incredible world building. I normally shy away from any fantasy but his city of last chances trilogy (now turning into a quadrilogy/on its was to 5??) is one of the absurdist Pythonesque and actually funny series I’ve read in years (although the first one is legitimately hard to parse/read given the style). Still, the juice is worth the squeeze and the second in the series I found hilarious.

I got a student subscription to cursor and after giving it a good 6 hours I’ve abandoned it.

I extremely dislike the way it goes forth and bolts. I don’t trust these tools enough to just point it in the direction and say go, I like to be a human in the loop. Perhaps the use case I was working on then was difficult (quite old react native library upgrade across a medium sized codebase) but I eventually cracked this on Claude; cursor in both entropic and Gemini left me with an absolute mess.

Even repeatedly asking the prompt to keep me in the loop it kept on just running haywire.

The difficulty is stopping when control of the organism is actually achieved, not just when you ‘feel better’. Most people are totally unable to make this judgement

Huntingtons is not unique but certainly notable because it is caused by repeat sequences and therefore uniquely suited to mRNA silencing in this manner. There are very few other progressive (and I presume you also mean neurological) conditions, but also applied to the rest of the body, where this is the pathophysiology. For example, currently there is no immediate expansion of this to ie Parkinson’s (different pathophysiological basis) Lewy body (although maybe?) alzheimers (again possibly depending on whether it is tau, amyloid beta or simply ‘type 3 diabetes’) and nothing whatsoever for vascular dementia or ALS

Have a read (rather than guessing) - it’s fascinating! Your other reply has a good insight but on more of a related topic but the primary reason this exists is for error correction. So approx one third of single nucleotide mutations have no change on the expression of the DNA or protein. And some of those that do change the amino acid are actually conservative; ie changing a basic amino acid to another basic amino acid which may still end up folding in the same way

In the US and much of Europe, the subsidies are to NOT produce, not to produce more

what exactly are you going to do with a spot hs-CRP?

Bad guess, I am not sure what OP really intends (perhaps you don’t consume whilst you sleep?!) because as you probably are starting to remember from primary school your body maintains homeostasis by continually respiring. It doesn’t suddenly decide to take a dump.

Ok, it does, but even when it does that, in order to do that it has been continually maintaining homeostasis

Here you go: https://drive.google.com/file/d/1y3_fgi0prAUjLugQWUDylZL_TN8...

There is no issue with countries buying us treasuries. They sail off shelves. Until the current administration started to make it look like there’s a possibility that the country may bankrupt itself, which threw a risk component into US debt for like the first time ever

Photosynthesis in nature is 1% efficient so it doesn’t need to be greatly better to beat it

The characteristic ‘jagged lines’ of aura is not at all related to the characteristic visual flashes of retinal detachment which an entirely different pathophysiology. Given that the advent of the flashes are new and related to exertion however it wouldn’t be unreasonable for the OP to keep a log of onset and duration and consider neurologist referral if they were to become more common with consideration for screening imaging as there are certain conditions related to exertion that can trigger aura

I couldn’t agree more, but as a 12 year old fingerprints of the gods got me started

The levels of fluoridation in order to cause difference in IQ as I understand it, from the Chinese studies, suggest that basically the effect if true occurs at around 2x+ the concentration found in supplemented water supplies.

My understanding also is that if you’re a dentist wanting to get rich, move somewhere that has unfluoridated water.

Who do you think conducted those peer-reviewed systematic reviews? I'm sorry if I don't take the word of some random guy's dentist over multiple meta analyses in major medical journals.

I don’t understand what you mean here. Are you just wholly rejecting the concept of expert knowledge, trials, meta analyses, basically the foundations of science, just because in order to participate in it you have to have tainted yourself by rigorously studying it?

Wouldn’t you rather have a player concerned with worst case scenarios?

Whilst this would be great, can I just temper this with a little understanding of how significant some of the side effects of the immunotherapies can be. There are significant limits on how much you can stress an already significantly stressed body and immunotherapy side effects can be WILD

I haven’t had an issue with Aussie cards?

But I still hit limits, I use Claudemind with jetbrains stuff and there is a max of input tokens (j believe), I am ‘tier 2’ but doesn’t look like I can go past this without an enterprise agreement

Yep that’s pretty much it as far as I know. I think they’ve been floated as the deployment mechanism for the SunSolar/sunCable powering Singapore from the NT (…if that ever happens)

I think it comes in pretty useful at temporary sites and for disaster relief but not sure if it’s been deployed for that yet

Dealing with the drug interactions when prescribing paxlovid j find to be a bloody nightmare. Must have handed it out like 10 times in my last run of shifts

There is also this company [0] The founder is a friend of mine and they’re growing very quickly particularly across mining and remote sites in Australia.

Interestingly he said the efficiency loss from having panels mounted at the ‘wrong’ angle is essentially nothing particularly when you consider the increased density and reduction in site prep/installation. They can literally install a couple hundred kW in an afternoon

[0] https://5b.co/

Not exactly your question, but it is well established that chewing/gnawing as a (young) child is directly proportional to jaw length (I guess you could say prognanthicism to some degree) - but specifically the amount of space available in the mouth for teeth. People who chewed/gnawed on ie a rug or something as a child are less likely to have crowding in their mouth and more likely to have eruption of wisdom teeth without an issue. This makes sense - using your muscles in these ways especially during significant developmental stages changes the release of trophic factors which in turn change development.

Really it’s no different from how someone who uses their body differs from someone who is sedentary all the time but in this case the timing of the ‘intervention’ causes big downstream changes

Thanks. couple hundred clicks to go but successfully downloading the files

I left my kindle in a train in Italy last week… am I boned?