nimz

Not many fans of The Office I see :)

Why tip someone for a job I'm capable of doing myself? I can serve food, I can drive a taxi, I can and do cut my own hair. I did, however, tip my urologist.

The way I tested it was to create Share link, then navigate to it in an incognito window on Desktop and try to RSVP. I am still unable RSVP without login. Perhaps it works without login if you explicitly invite a certain email.

I tested it with a sample event and I don't see any way to RSVP without logging into an Apple account. Maybe I'm missing something?

Whoa, I'm doing the exact same thing right now for my son, and using Gmail as well.

Blessings to you for this warning. I'm going to do something about changing the location of this mailbox asap.

In the late 80s/early 90s when I was kite-battling, it was common to use these glass coated strings. I haven't played in decades, but it does seem quite dangerous now that I think about it as an adult. I'm glad the practice is banned.

We live in a different age today in terms of safety awareness. I vividly remember playing with powerful fireworks during Diwali celebrations. We'd light them in our hands and hurl them skyward moments before they burst. Today the mere thought of this makes me shudder, and I can't even imagine my children playing this way.

In my youth, I participated in "kite fighting," a popular activity in my home country. During these battles, opponents maneuver their kites, attempting to cut each other's kite string through tricky aerial tactics. We used special kite strings coated in thin glass. The victor's prize was getting to keep their opponents kite. Around January, during the kite festival, there would be hundreds of kites in the air all dancing or playing with each other. A magnificent sight.

Your point is valid - we shouldn't take single-country risk in investing. Assuming you believe the world as a whole will get more productive and value creating, globally diversifying your stocks is the answer.

As an example that supports your point, the Japan stock market (Nikkei) peaked in 1989 and STILL has not returned to that high.

However, even if you were incredible unlucky and had bought in at the 1989 peak in Japan, if you had an internationally diversified portfolio, you would be OK. E.g. a 30/30/20/20 Jp Stocks/Intl Stocks/Jp Bonds/Intl Bonds portfolio purchased in 1989 at the Nikkei peak would have more than doubled by 2014 (see here: https://www.bogleheads.org/forum/viewtopic.php?t=265807 and also https://www.afrugaldoctor.com/home/japans-lost-decades-30-ye...).

Congratulations on the launching to real users. I know how challenging that is and especially when your users are kids, I can imagine the pressure is much higher.

One piece of feedback on your use of the term AI. While adding the term "AI" to the description of /most/ products seems to increase their appeal, in products that are for children, to me, it reads like this product will be buggy at best and ends up decreasing the appeal. Words like researched, "smart", advanced, cutting-edge etc may be better suited. This is just one person's reaction, of course. I could be wrong--perhaps to non-engineers, reading "AI" on kids' products now has a more positive reaction.

A "real" demo video was exactly what I was looking for as well. Since the concept is so novel, seeing the product in action would increase my trust, and willingness to buy significantly. My skeptical side made me wonder if demos with real children had been left out on purpose so it doesn't make the product look bad - probably not what you were going for.

The 50th anniversary of this day passed barely a month back. Pretty cool.

Here is a more detailed NPR Segment on this story with pictures: https://www.npr.org/templates/story/story.php?storyId=114280...

In addition, UIUC closed their in-person MBA program not long ago. Maybe a sign of things to come?

https://www.insidehighered.com/quicktakes/2019/05/28/illinoi...

This version has a more nostalgic video: https://youtu.be/5zA1Zkz5DUE

The topics aren't perfect either, unfortunately. For example, Sublime Text, as we know it, was first released in 2008 while the topic trends data you linked shows it being the leader in 2004.

Great to hear and congratulations to the team. Amazing persistence. I used to be a huge Textmate fan - it was so revolutionary in its time. Unfortunately, I think it is too late. The Google Trends comparison of Textmate, Sublime Text and VS Code tells the story: https://trends.google.com/trends/explore?date=all&geo=US&q=%...

You must have taken the standard RIPE therapy which consists of 4 powerful drugs: rifampin, isoniazid, pyrazinamide, and ethambutol. Plus sometimes doctors add some other pills to control specific side effects a patient may be having like nausea or dizziness.

I really appreciate you adding your personal perspective. A big problem in TB today is that the “western” world sees it mostly as a “not-my-problem” kind of disease. What people forget is that TB is airborne and that the world is getting smaller. It will start impacting everyone.

TB is everyone’s problem and more investment should be made by the wealthier countries toward it’s care.

True that they're being cautious to protect their investment in the drug. In the case of TB, it's taken seriously enough that the drugs used to treat MDR/XDR TB are taken under close medical supervision, especially brand new drugs like Bedaquiline and Delamanid. They are usually administered under DOT (directly observed therapy) where a patient is required by law to take the drugs daily in front of a witness, or with lower-risk patients they use VDOT (Video Directly Observed Therapy) where patients can use an app to video record themselves taking the medicine daily and submit the evidence to the local Department of Health. In cases where patients don't comply to treatment, they can be arrested and isolated due to the public health risk.

The reason is that in some trials of Delamanid, a rare but serious side effect called QT prolongation was uncovered. To monitor for this side effect, a patient needs to have regular EKGs done. Since Delamanid is not approved in many countries yet (including the US), Otsuka wants to eliminate even the smallest chance of a patient complication which could delay their approval process. So they call for full hospitalization while the patient is on the drug.

For brand new drugs that cure critical illnesses, the FDA has a compassionate use program (officially called Expanded Access) which allows drugs that are not fully approved yet to be used immediately by very ill patients. Otsuka requiring months of hospitalization to monitor for a rare side effect was just wrong and against the spirit of compassionate use access IMO. This side-effect is easily and cheaply monitored by regular EKGs at a local primary care doctor or urgent care clinic.

This advancement is especially promising because access to Delamanid (a drug similar to Pretomanid) is very difficult for patients in many countries. The company that developed Delamanid, Otsuka Pharmaceutical, has been extremely restrictive in allowing access to it.

I know someone critically ill who was petitioning Otsuka for access to Delamanid under compassionate use, but Otsuka would only agree to give access if the patient stayed in a hospital for 4-6 months. This is just a crafty way for pharma companies to refuse access since they know the cost of months of hospital stay is not affordable or practical. Luckily in this instance, TB Alliance and others fought with Otsuka to get this patient access to the drug.

In many high-need countries (India/Africa/China etc), desperate doctors frequently just lie to Otsuka about the patient staying in the hospital in order to get access to the drug.

Opening access to Pretomanid is a great advancement!

That is certainly possible. However, the trick here is hidden in your saying the idea is "fully fleshed." Our temptation often is to fully flesh ideas either in our own imagination, with our friends, or with internet research. If instead you actually flesh out ideas by speaking to customers, building prototypes and testing them, gathering real user data, and even actual sales data, then definitely yes that idea could be worth a ton. But if this idea is fully fleshed out like in a research paper where you've spent 24 hours in a library, then your case is much harder to make.

You mentioned attracting co-founders so just adding one important piece of advice: don't be stingy about equity with your co-founders. Even if you were the one who came up with "the idea," or worked on it alone for a few months.

When your company is actually worth something down the road, you will both be wealthy enough, however, in the early stage, when your company is worth close to zero, one of the highest risks is the founder relationship/compatibility. When all partners have equal ownership, there is a much lower chance of having passive-aggressive power struggles, and grudges.

A toxic, deteriorating co-founder relationship will almost surely kill your company too early, whereas being generous early will be something your co-founders will never forget and it will pay back multifold overall.

$20K is a very low estimate for cost of owning a car. Edmunds estimates the 5-year "True Cost to Own" of a Toyota Camry for home-use is $35K. This is based on a 15K miles a year, Uber drivers can easily put on 50,000+ miles a year.

Interesting list, thanks!

Feedback: All of your Amazon links go to amazon.in. Not necessarily a bug, but Amazon doesn't automatically switch to my local Amazon (in my case amazon.com), and so I end up copy pasting the product name into a new tab, that may end up in less referral revenue for you. You could geocode the user's IP serve them appropriate Amazon links.

In long term, this could change everything. In the short term, the tech is cool but I'm having trouble imagining how I would use this.

In the short-term:

Would I set this up at home for personal use? Likely not as I would have my laptop already for this purpose. At home, I would want the flexibility to be able to move between my desk and couch, at least.

Would I use this at work? I already have a powerful work laptop - this would definitely not substitute.

If my employer had many traveling employees, would they setup DeX workstations for those who are visiting for a few hours? Maybe. For work use, it's too limited in power and applications to be a serious competitor.

In the long term: If I were a casual user of tech, whose primary needs were email, documents, videos and photos, would this let me not buy a separate laptop altogether? Yes - possibly. This is the killer use case. Eventually, the phone will get more and more powerful and internet speeds will get faster. For the casual tech user of email, documents, media and web browsing, this will more than suffice. Having two machines to buy and maintain, that do the same thing for you, will seem clunky and out-dated.

Veteran podcast hosts speak relatively slowly, so that it allows for the widest range of listening speed comfort levels amongst their listeners. People can then use their podcast player to customize how fast they like to listen. This is an easy way to tell apart the experienced and inexperienced podcasts.

To anyone who found this link interesting, I highly recommend picking up "The Signature of All Things" by Elizabeth Gilbert (yes the author who wrote Eat, Pray, Love). The Signature of All Things is historical fiction novel about a botanist who is fascinated by moss and her research leads her to discover evolution independently of Darwin.

New York, NY | Fullstack Academy (YC S12) | Full-Time & Part-Time JavaScript Instructor/Engineer

TL;DR: We're looking for multiple instructors for our part-time and full-time courses in New York. If you've always enjoyed teaching/mentoring people, this will truly be your dream job. Positions open for our weeknights/weekend course and also for Full-time positions. Contact nimit@fullstackacademy.com to express interest.

Fullstack Academy is an Immersive Software Engineering school in NYC. We are one of the most selective such schools in the country. Our students are passionate and smart and fun. You'll also get to work on building cutting-edge educational software. We also just moved into an awesome new campus in Manhattan.

Interested? Contact me at nimit@fullstackacademy.com or apply at http://bit.ly/teaching_code_makes_me_happy

You weren't, you got me addicted to Joe too!

Unless you're an investor, nothing much to lose by doing so if the speaker is actually interesting and you really want to meet them. Alternatively, you could always sign it Mickey Mouse!

Hmm, random question, did you work at Yahoo around 2005-08?