j2d3

All this was an excuse to use the word brobdingnagian.

This reminds me of the lifetime movie classic starring Mare Winningham, "Who is Julia?"

Them too, but heroku runs on aws and basically provides this, too, but instead of free, it's very very expensive

This destroys heroku, right?

I checked and it's corrected in the most current version:

https://github.com/s3tools/s3cmd/blob/master/s3cmd#L2048

The version I have with the typo is 1.5.0-alpha1

ok, that makes sense! S and C are fairly close together on the keyboard.

Pretty funny typo ;)

Tamiflu is made by Gilead. Donald Rumsfeld was on the board. Mexico (among other countries) borrowed millions from the world bank to buy Tamiflu during the H1N1 craze.

http://www.nybooks.com/articles/archives/2011/dec/22/world-b...

I say all this to suggest that it's not a waste of taxpayer money by uninformed politicians... no - the politicians are very well informed.

CEO is inherently a political role - a CEO is the face of the company. If the CEOs political views are at odds with most of the employees of the company as well as the company's product's userbase, it's hardly surprising that there would be a movement to get him out. He's the face of the company. If that face is ugly / mean, then he's probably the wrong choice for CEO.

...that said, I do like the idea - have a 3 year old, and trying to understand what is available out there is incredibly difficult and haphazard.

"Expedia for..." sounds pretty weird. Think of something else. I can't remember what actual Expedia is for.

There are many millions of people who have HIV but not AIDS. Their immune systems work well, and their viral levels are controlled by medications. These people are on US health insurance and are highly monitored already, and easy to enroll in studies, easily accessed and monitored - as they already conform to an HIV medication regimen and see their doctors regularly.

Why would a company not test a technology that may well benefit both infected and uninfected people on both populations? You would only have more data. It will take much longer to see the results if you are only studying it as a preventative measure because you have to wait (a really long time, I would suspect) to see which of your study ends up getting HIV. Additionally, you'd need to study those that do get HIV (if some do, and some probably would, as even the best vaccines aren't 100% effective) and try to see if you can tell if their infection progresses differently or if it is somehow augmented by the vaccination's boost to the immune system. I mean... your explanation doesn't actually make that much sense to me.

Why not test both populations?

This story discusses other HIV vaccine efforts that are targeted at already infected and stop the dependence on the HIV meds:

http://www.livescience.com/18107-hiv-therapeutic-vaccines-pr...

according to that article there are 34 million people already infected worldwide.

Hi Howie, can you elaborate? You didn't really address the why / why not aspect of the question.

Since the Immunity Project concept relies on training the immune system to mount a successful response against HIV, why would it not present some benefit to an already-infected person whose infection is otherwise controlled with drugs?

You may just be focusing on the preventative aspect, but there are many millions worldwide who are concerned with controlling HIV without depending on expensive antiviral drugs that in many cases are completely unavailable.

One of the wonderful things about the internet is that no one knows you're a...(something you're not)... unless you tell them.

And op's point is that we do not have an open market due to ill conceived regulations like dodd frank.

I thought this was going to be a joke post along the lines of "disrupt threadmaking" -> "disrupt sewing machines" -> "disrupt sweatshop labor issues" -> "disrupt textile design and manufacturing process cycle" -> "disrupt fashion industry" -> "disrupt ecommerce" -> "disrupt logistics"

"Because we’re in this transition period between PHP and Ruby, we couldn’t use PostgreSQL on Heroku because PHP doesn’t speak PostgreSQL."

sigh

Do people really pay $250k to engineers right out of college, or is that an exaggeration?

Um, actually, on the other hand - re: Sangamo Genetics: http://seekingalpha.com/article/1705622-sangamo-a-fiery-biot...

Yikes!

This approach seems roughly similar to what Sangamo Genetics has been trying for HIV - with some recent success - http://www.aidsmeds.com/articles/Sangamo_genetics_1667_24579...

What if we tied a basic income to accepting 24x7 monitoring of the body and all communications from the body's point of view in space... i.e., a monitoring band that tracks health biometrics, as well as audio and video, ambient temp, humidity, etc. - full instrumentation of each individual who opts in.

The monitoring band would also act as the recipient's communicator (smartphone) - so - they can freely use it to call, text, email, get apps, etc., it's just that all the data they generate - each individual participant's trace - is recorded.

The massive amount of data collected from people willing to trade a homeless lifestyle for one with a steady income would have tremendous value in aggregate, and be unavailable to anyone for nefarious purposes. The only thing you have to do to get the basic income is be willing to have all your data recorded (but not shared publicly!)

Your anonymized data will then be made available (along with everyone else's) via an API to developers of apps, and, assuming you give them permission, they will be able to access your sensitive / personal / private data as well.

I dunno, Paris h. as media hacker could actually be an interesting discussion.

This is probably bound to catch on fast in the us where teachers and their unions are thought (by an unnerving possible majority) to be one of the primary factors in our ongoing economic problems.

This seems more like your observation rather than a point of the article, but I agree 100%

So far there's nothing to stop!

This article is overly focused on cost, which is dumb because they're in development. Clearly costs will not be the same when they become generally available, and the ownership model is going to change completely, too. Car service on demand will largely replace car ownership.

Cheaper, but fairly ridiculous. Stay in Barcelona and telecommute.

Similarly, it would be cheaper for me to rent in Mexico City and commute to my job in Los Angeles. Yes, some global metropolises have lower rents than others.

Car makers fear and will do whatever they can to stop autonomous cars as they represent an existential threat to their business. We will need an order of magnitude fewer cars in a world of cars-aas, on demand cars... it blows away the entire industry. .. People are, I think, underestimating just how sweeping the shift would be once it actually gets fully underway. It is not an incremental change... It's like the shift from horse and Carriage to autos... That big or bigger

actually, I take it back... what you're saying is not the expected use case. you want to use it as a snack food (maybe), when really its intended to be a default food, but that doesn't mean you should only eat soylent ever. They want to make something that you can eat exclusively workout endangering your health. I don't think they actually expect everyone uses it to only use it exclusively.

Not sure, but I think this is the expected use case. Soylent is supposed to be something you can eat exclusively, but also, I don't think even soylent creators expect their users to eat it and nothing else ever. I plan to replace "mindless" meals with it, but eat delicious, healthy non soylent meals when I have time and inclination. Many times I eat stuff I dont want that isn't healthy due to time constraints.