gavinray

There was actually a VERY recent study on mega-dose creatine for sleep deprivation:

  > "Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation"

You need a dose high enough to penetrate the blood-brain barrier, around 0.3g/kg (so ~30g for a 100kg person).

Seems to be missing the "why" over Kotlins native WASM support (which is very mature)

The official Kotlin playground uses WASM, for example (JVM drop down-> choose "WASM")

https://play.kotlinlang.org

It got the 3D effect of leg behind the bar at least which is impressive

MULTISET is the SQL native way of doing this but it's only implemented in Oracle, and most people have never heard of it

jOOQ emulates this feature for arbitrary databases and has the best explanatory article on the web about MULTISET imo

https://www.jooq.org/doc/latest/manual/sql-building/column-e...

The closest thing I know of, is that there was a concurrent queue algo called LCRQ

It originally required double-width CAS, but IIRC in recent years someone figured out how to remove this to make it more portable

Best reference I could find from cursory google:

https://ppopp23.sigplan.org/details/PPoPP-2023-papers/2/The-...

ResearchRabbit is free and has this feature!

https://www.researchrabbit.ai/

ConnectedPapers also has this but they started to limit unless you pay:

https://www.connectedpapers.com/

A few other ones I know of:

https://litmaps.com

https://consensus.app/home/features/citation-graph/

His primary interest nowadays is LLM's. Unsure if he gets paid for it, but he seems to take it as a dayjob.

Neat! Two questions I had after using it:

1) Is there a way to filter the visual atlas by the search term? For instance, I searched "ribosome" and it gave me a list, but I couldn't seem to visualize the list

2) I notice there's an MCP tool. I've used https://paperclip.gxl.ai/ in the past to good effect, curious if there are any standout features from tomesphere?

Despite Muse being relatively average, I've actually used the Meta AI webchat LLM since it released.

The reason: Its writing style feels "unique", and I find it pleasant to read for science-based topics.

I never ask _ONLY_ Meta AI, but the answer it gives is almost always in a distinctly different style than other frontier LLM's.

I think this is because of the unique JEPA architecture they have, but that's a layman's hunch.

Why would you apply to a job for a company you don't even know what they do?

I have paid personal subs to ChatGPT, Claude, Grok, Gemini

For science (primary biology/pharmacology) questions, Gemini 3.1 Flash Extended produces the answers I _personally_ find "best", in terms of content, phrasing, and formatting.

What a brilliant idea, neat. Thanks for the link.

Benzedrex is not l-Methamphetamine, it is Propylhexedrine

This is straying a bit from the original post, but agreed, NMDA antagonists and related compounds effecting glutaminergic tone are showing promising directions.

N=1, I've had very positive experiences with DIY Auvelity, using 150mg Buproprion XR that I'm RX'ed with 60mg OTC DXM-only tablets.

"DXM does nothing", proceeds to link a study whose contents describe significant decreases in cough severity versus placebo.

I am convinced that many people ask LLM's "give me a citation URL" and don't bother to read it.

"Reverse brain aging", sure, in the same sense that taking Vitamin C reverses aging.

The nasal spray reduced markers of inflammation in hippocampal microglial cells.

A lot of things reduce inflammation. That is not "reversing ageing".

Of course, "reduces inflammation" doesn't headline very well...

The described "attack" would not work, due to not triggering an HTTP request.

When an LLM generates text, it does not send requests to URL-looking strings it generates to validate they are real/live.

You'd never get your "ping" request.

  > The LAST thing you want is a non-deterministic process monkey patching your code.

Posted prices of Chinese gray market bulk peptides on Twitter recently

It's $95 for 10 vials of 30mg Tirzepatide, which at the highest dose of 15mg/wk, is still 20 weeks for less than $100...

https://x.com/GavinRayDev/status/2067348581418434564/photo/1

Finnrick will even test your peptides if you agree to them publicizing the results and the vendor:

https://www.finnrick.com/products/tirzepatide

It's just DLSS/Frame Generation for MRI's.

I consumed +11lbs (5.1kg) of food yesterday for only 2,500kcal

If you have a stomach and appetite that are capable of consuming the 15 to 20 lb you need to eat 3,500 to 4,000 calories of similar foods, you ought to call a research lab

It appears as though the WASM decode returns two values -- one indicating the data type as a primitive value, and a second value being the data buffer

Then there is a helper in this case to de-serialize, "primitive_array_from_buffers()"

https://github.com/future-file-format/F3/blob/bd92506447dc13...

WASM runs in a confined memory space allocated for the program. There is no I/O or host address space access.

You need to run a WASI environment for that.

  >  the attacker can embed whatever WASM payload they want into the file since the file will be “opened” by “execute this offset into the file”.

WASM physically cannot interact with the underlying host or perform I/O -- you need a WASI environment for that.

I guess it's a good thing that the F3 standard does not say "read this file and execute the instructions you find at the beginning", then?

The WASM encoders/decoders are embedded resources that exist as byte offsets in the file metadata, not header info.

Double-clicking an ".exe" (or running it via a shell) is not the same as "bag of bytes", it's "send these bytes to an executable environment".

Doing `head foo.exe` is quite different than `run foo.exe`

If I encode executable instructions in "image.png" and then send them to an interpreter that runs those instructions, the file extension doesn't matter.

Many languages don't have ergonomic experiences for working with C ABI's without explicit wrapper code.

Hell, Node.js didn't even get this ability until LAST MONTH:

https://nodejs.org/en/blog/release/v26.1.0

You'd have to write a second library to interface the C ABI with Node via NAPI just to consume it.

There is no concept of "executable" vs "non-executable" content in a file.

A file is a bag of bytes. You can send those bytes to different things, like a text editor's content-stream, or as the input to a WASM interpreter.

What you decide to do with the bytes in a file is your own prerogative. Each byte is whatever you make of it.

This bit is quite genius, rather than depend on a language-specific SDK/lib for working with the formats you can fallback to exported WASM methods if none exist:

  > "Each self-describing F3 file includes both the data and meta-data, as well as WebAssembly (Wasm) binaries to decode the data. Embedding the decoders in each file requires minimal storage (kilobytes) and ensures compatibility on any platform in case native decoders are unavailable. "

Equivalent of Trusted Access for Anthropic is "CVP" (Cyber Verification Program)

https://support.claude.com/en/articles/14604842-real-time-cy...