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dqh

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Cortical Labs CTO https://corticallabs.com

NakedJSX creator: https://nakedjsx.org

Versatile Commodore Emulator (VICE) dev team

david.q.hogan@gmail.com https://www.linkedin.com/in/davidqhogan/

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Perfectly for me I guess I should have said. Nonetheless, this md file packaging mistake suggests that at least once they’ve fallen into not reviewing changes properly, and I wonder if that lack of discipline is more widespread. I hope not, otherwise their ability to deliver on their privacy promises will be compromised.

I’ve been wondering if vibe coding was responsible for the recent introduction of acoustic echo cancellation (AEC) bugs in FaceTime (muting and unmuting the microphone appears to temporarily fix it). Apple has always had excellent AEC in my experience, it’s sad to see them breaking a fundamental phone function.

We'll likely leave the answering of your equivalence question to our users. While we do plenty of internal research, the primary goal of our cloud platform is to dramatically expand access to this field. There are no doubt many low-hanging fruits to be discovered.

It's not the case at all - years ago we tested Pong with human neurons vs mouse neurons, and human neurons performed better. More importantly, they allow the study of the effect of external interventions (such as trial medicines) on the learned function of human neurons. So we spent years building a machine and software platform to facilitate this sort of research.

The Doom project is mostly a bit of fun that demonstrates how quickly someone new to the field can see real results with our platform. Our data scientists believe that biological learning was demonstrated in this case.

Thanks!

We focus on using real neurons, I'm not aware of a software based equivalent. But users can `pip install cl-sdk` to get started with our API. The SDK is still early but supports playing back a recording of real data so applications can be built with a realistic spike frequency. (We'll be releasing a set of recordings for this)

Cortical Labs CTO here. My focus is on the system itself rather than applications, but for what it's worth ..

When the neurons didn't get stimulated by the application, performance did not improve. The only explanation our data science people has is that the neurons began to learn and perform the desired (highly abstracted) task of 'playing Doom'. This was not a surprise as we've shown this before with a version of Pong using a different platform. We built the CL1 and the CL API to enable rapid iteration on this sort of work.

One benefit to this is that when you have a measurable learning effect, you can measure this before and after exposure to an experimental drug or other molecule. It becomes possible to test the impact on neuron function, not just survival.

The neurons live on an electrode array kept inside a machine which keeps them alive (body temperature, sugar, gas, etc). The embedded system continually measures the voltage at each electrode, and can electrically stimulate the neurons via the same.

Users are provided with an easy to use Python API that allows realtime observation of the raw signals and of detected action potentials (spikes). They can also execute precisely controlled stimulation sequences, which allows information to be presented to the neurons. Then there are a lot of higher level application APIs to handle things like recording data, real-time visualisation, and experiment config management.

Why: it appears to be possible to teach neurons to perform tasks (we taught some to play pong several years ago). Since then our focus has been on building a system that enables rapid iteration in this sort of research. We're selling the system to organisations that have the appropriate biology skills, and renting access to hosted devices where we provide and take care of the cells.

I work on the software stack for a biological computing platform (think: tool for programming with human neurons in a dish).

Coding work spans FPGA (SystemVerilog), Linux kernel C, userspace C, Python, and yes, some web services and Browser JavaScript also. I also work on the network engineering of the cloud service and on the Linux OS image.

Easily the most fun I’ve had as a developer and I’ve worked on lots of different types of commercial software projects before. Not all the world is web apps, embedded work can be very satisfying if you’ve not considered it.

I've never liked the idea of community actions in the critical build path, so I use official actions/* when I can, and otherwise use actions/github-script to invoke the GitHub API via inline JavaScript when I can't.

This is in spite of having a long list of technical accomplishments and an impeccable public track record under my belt.

If skills aren’t the problem, one possibility is that a rigid attitude, lack of humility, or something like that is rubbing interviewers the wrong way. Please forgive my unsolicited advice and good luck with the search.

VanillaJSX.com 2 years ago

Those interested in this space may find my fairly unknown project interesting: https://nakedjsx.org/

It started as a static site generator but added a bunch of support for client JavaScript too.

I’ve been continually using Linux for various purposes since the late 90s, and recently wrote a non-trivial kernel module for an embedded device. So I’m veteran-ish.

I tried Ubuntu on my MBP because I thought its popularity would mean the best chance of things working out of the box. I’m long past having time to spend on getting basic things working.

Are you involved in the still-thriving C64 demo scene at all? Possible way to reconnect with the magic if not. Especially by attending (in-person, ideally) one of the many demo parties around the world.

There are also parallels with embedded device and FPGA work that I personally find thrilling.

Plus we on the VICE (open source Commodore emulator) team are always looking for devs.

I was hired for my current role at Cortical Labs via a “Who wants to be hired?” thread a year ago. First time I had tried via HN, I had a great experience and I recommend trying it if you haven’t.