As someone who tried to build a fairly large project with HTMX + Go, I can say it just wasn't there for me. Maybe it will get there eventually, but I'm not convinced.
For simple CRUD apps and admin dashboards, HTMX is great. But once you have lots of interconnected components, shared state, and complex interactions, managing everything quickly becomes difficult.
I originally chose HTMX because I really didn't enjoy working with React. Eventually I tried SvelteKit, and it completely changed my perspective. I still use Go for the backend, but SvelteKit in SPA mode for the frontend. It gives me a clean separation between the two while making complex UIs much easier to build and maintain.
What really sold me was that Svelte feels like a natural extension of HTML rather than a different language with JSX. State management is simple, the component model is intuitive, and the new `$state` syntax is especially nice.