HN user

ALee

7,492 karma

Partner @Initialized.

Fomer CEO/Founder of Esper, previously Director of Product & Senior Advisor to U.S. Small Business Administration (and White House). Before that, I worked on FarmVille, because Zynga acquired my startup JamLegend (think guitar hero online).

Prior to FarmVille and JamLegend, I created Fantasy Congress in college (featured in NYTimes, CNN, NPR, etc.), Kingmaker- an election predictions market, and then Poliquiz.

Twitter @ndrewlee

Posts1,323
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twitter.com 3y ago

No global democratic decline- Subj and obj measurement of democratic backsliding

ALee
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az.swoogo.com 3y ago

Crypto Startup School

ALee
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a16zcrypto.com 3y ago

Crypto Startup School: relaunched and expanded

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aeon.co 4y ago

Evolution is not a tree of life but a fuzzy network

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aeon.co 4y ago

Evolution is not a tree of life but a fuzzy network

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www.sfchronicle.com 4y ago

8-year-old’s plan to sell Girl Scout cookies turned into lesson on Doordsah

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www.autonews.com 4y ago

Why GM's Mary Barra Dismissed Cruise CEO Daniel Ammann

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www.buzzfeednews.com 4y ago

We Found the Real Names of Bored Ape Yacht Club’s Pseudonymous Founders

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www.businessinsider.com 4y ago

Slides: Major Peloton Investor Eviscerates CEO John Foley

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www.smithsonianmag.com 4y ago

Lost languages discovered in the oldest continuously run libraries (2017)

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www.space.com 4y ago

SpaceX launches 51 Starlink satellites in first West Coast launch

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www.bloomberg.com 5y ago

Foil Maker Reynolds Sees Three Rounds of Price Hikes in 2021

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www.thecrimson.com 5y ago

The Crimson Klan

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jalopnik.com 5y ago

When Adobe Stopped Flash Content from Running It Also Stopped a Chinese Railroad

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aeon.co 5y ago

For Hannah Arendt, totalitarianism is rooted in loneliness

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meltingasphalt.com 5y ago

Crony Beliefs

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www.nytimes.com 5y ago

Life Without Amazon (Well, Almost)

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arstechnica.com 5y ago

Electric lighting changed our sleep, and other stories in materials science

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www.bloomberg.com 5y ago

Psychological Torture: The Alleged Extortion of a Venture Capitalist

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civileats.com 5y ago

Now Legal for Home Chefs in California to Sell Meals

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thefinder.medium.com 5y ago

A Statement on the Disclosure of My Identity

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ideas.ted.com 5y ago

People’s words and actions can shape your brain

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www.npr.org 5y ago

Caste discrimination in some of Silicon Valley's richest tech companies

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medium.com 5y ago

Descript Video and Screen Recorder

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www.thetimes.co.uk 5y ago

Dyson reinvents university with its own degrees

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arstechnica.com 5y ago

Going all-in on remote work: The technical and cultural changes

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www.smithsonianmag.com 5y ago

Lost languages discovered in the oldest continuously run libraries (2017)

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www.npr.org 5y ago

Rare Meteorites Show How the Earth Got Its Life-Giving Water

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www.theverge.com 5y ago

Game of Thrones Showrunners Are Adapting the Three-Body Problem with Netflix

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www.archpaper.com 5y ago

Autodesk issues a response after architects speak out over Revit

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I wonder how much of this labor is a choice between online labor versus choosing not to work retail where the profit is a lot lower, meaning your take-home is equal to your costs.

Let's assume that you can make a reasonable living in a different part of town instead of commuting to a service sector job. Add on top of that, you get to control your hours and there also seems to be more and more foot traffic in that part of town. As you start moving to that part of town, you realize that it's so much closer to your work that you save money on transportation and you have free time to pursue investing or other ways to better yourself. I don't think we would ever have issues with labor moving to better parts of town, right?

The only issue is that this better part of town is the internet. I wonder if the larger long-standing effects of COVID were an experiment on the general population that they could make money outside of what they've been told.

Technically, Olympic sports are niche sports as well - the only difference is they have a giant collaboration every four years. There's nothing to say that disc golf won't be part of the olympics or bowling (addressed in the article as well)

In my 10+ yrs in this industry, it's astounding how many founders we've lost trying to hack Maslow's hierarchy. I'm not against drugs, I'm against addiction because it is terrible, destructive, and so short-term.

Founders, you're not Peter Pan, your shadow stays with you no matter how many lost boys you surround yourself with. Such a tragedy that he was taken away from us too soon

Recent New York data during a slowdown paints a different picture:

"De Blasio, in this sense, is a remarkably unimaginative politician, like Andrew Cuomo. Police did stop doing their jobs, momentarily, after the murders of Liu and Ramos, in protest of de Blasio’s allegedly anti-police gestures. Arrests and summonses plummeted in early 2015. This, in labor and political parlance, is called a slowdown. The truth about the slowdown, as I’ve written before, is that crime remained quite low. Lack of police enforcement did not unleash the sort of disorder Lynch and his ilk always promise would come. It’s a small sample size, yes. But de Blasio has never used this data point to his advantage. Instead, he has grown only more defensive of his police department. Even in an age of COVID-19-induced catastrophe, with tax revenue evaporating by the month, de Blasio cannot bring himself to meaningfully cut funding to his police department."

Source: https://rossbarkan.substack.com/p/why-is-the-nypd-so-powerfu...

As I live and breathe - we're talking about ToshCo. I have shopped here, spent time in Gustavus, enjoyed the greatest July 4th celebration in the US here while climbing a grease pole. Funny thing is that not all the residents can buy stuff from ToshCo because it's more expensive, so they go to the local thrift store instead, aka Treasure store.

Dunno if this could be probiotics or it could be quack science. I think it's important that it warrants investigation (a double-blind RCT) - I always harbored hope that experiment.com could be able to create crowd-funded research for populations who are going to great lengths and using lots of resources for these cures.

Also, you're forgetting about the two following paragraphs after your quotes (which I just think is interesting to test in general):

Perhaps, instead of destroying the bacteria directly, the venom’s effect is indirect, kick-starting the immune system. Bee venom studies have shown promise in combating symptoms for autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. According to Justin Schmidt, an insect venom expert at the Southwestern Biological Institute, in Tucson, it’s possible that when the immune system begins attacking itself, an injection of bee venom may help by providing an alternate target—“something to chew on,” he said, “and this tends to regulate the immune system so it does what it’s supposed to be doing, which is attack toxins that are getting into your body.” While Lyme is a bacterial infection, it sometimes mimics autoimmune disorders, and so maybe, somehow, similar rules apply.

It’s also possible that the pain of the stings plays a role. “Maybe the venom is doing something to kick off pain receptors,” he said. Anecdotal evidence suggests that other types of venom may also work this way. A brief article in the Lancet, from 1983, described a 43-year-old woman in Arizona who had MS and went into remission for two months following a scorpion sting on her right foot. An immunologist in Houston told me she was contacted by a physician experiencing progressive MS who said he’d been stung by a sea anemone and went into temporary remission.

Herf - it would be great if you guys could have an official position on this paper and to really help us understand what flux is doing or not doing. I tend to see you folks as the vanguard pushing the bigger tech companies to adopt your technology - I for one tell EVERYONE to download Flux.

The problem with this is that the desktop computer being widely used is probably the late 1990s (and we should be isolating for screens that emitted the white light/blue light mentioned. Assuming that it takes daily exposure over a number of years say 20 years, we should probably start seeing that within the next 5-10 years from tech industry workers. It may be as severe as tobacco or as benign as fluoride, we'll see early indications, but we won't know until much later. I think everyone just likes it when it feels better for your eyes to filter out blue light.

Change your setting either with people or places. You're likely sitting at home or always on your computer doing the same thing. That's not helping anyone. If you change your setting it'll also change you personally. I echo everything else related to sleep, exercise, and diet, but besides that just go meet people or work out of different places. It'll work odd wonders because biologically you're predisposed that way.

Literally everything we do can be boiled down to checklists. Atul Gawande is a national treasure and I highly recommend his book Being Mortal as well.

Is it me or are we asking too much of our relationships? In the past, relationships were based on proximity more than anything else, but now int he world of endless choice, we seem to want more from our friends, our partners, our co-workers, etc.

I think the whole thing is just so tiring. I think almost everyone I know would do something if I were in trouble and if I asked them (to a point, I don't know anyone who would want to take care of me for a month - even myself).

I read recently that marriage is becoming the same thing where we want our partner to be EVERYTHING - the drinking buddy, the confidante, the psychological help, the travel partner... and supposedly that makes everyone unsatisfied with their partner because it's such a stupidly tall order. Do we hire people to do all those things for us too? On the other side though, if you find that person, you get REALLY good marriages. I would suspect the same is true with friendships. Instead of being worried whether a friend is a true friend, just relish that you have friends who can serve different purposes in your life and if you have a close one - enjoy it.

If the recent Zuckerberg testimony is an example, we need more public officials who can understand the complexity of code, technology, and the law.

I've known the young assistant attorney general in this story for more than ten years. Rob Sand is a great guy and is running to be a state auditor of Iowa - you can support him at robsand.com. Also, if you're interested in meeting him in person, I'm also happy to facilitate an introduction (friends across the country like to house him from time to time).

In a recent NYT interview, here's what she had to say about that: "[T]iming is everything... Yahoo’s offerings could consume hours a day, and trying to regain that moment in time was really hard... regaining that contextual relevance that was afforded to Yahoo in 1999 and the early 2000s was difficult."

Another data point - almost always the first thing that counselors suggest in couples counseling is to hire a house cleaner. It just seems that in a world where time is becoming even more precious, doing something you hate (e.g. washing dishes) just drains you even more and decreases the quality of the time you spend together.

Hey HN - author here. I've been on Hacker News for a long while, thought this would be useful for anyone who is dealing with difficulties in ML, enterprise, or just shutting down a startup. I included some serious nuggets on how to go about doing an acquisition, so happy to talk about anything. And to anyone else working on a "startup with no end" - I hope this helps you make the difficult decision to shut down.