HN user

subcosmos

1,568 karma

Health and Computer Hacker Obsessed with Longevity and Metabolic Syndrome

Prior training in Astrophysics, PhD in Biophysics Malware analysis and incident response

Posts25
Comments357
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github.com 1mo ago

Show HN: NeuroAnswer – MCP server lets Claude navigate petabyte-scale brain maps

subcosmos
3pts0
quarantine.infino.me 6y ago

Quarantine Home – A Docker container to help find Covid-19 drugs

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quarantine.infino.me 6y ago

Show HN: Quarantine-At-Home – a distributed project for finding Covid drugs

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www.youtube.com 6y ago

A Virus Can Make You Obese

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www.thedailybeast.com 7y ago

Millions of Water Bottles Left on Puerto Rico Runway for 1 Year

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www.businessinsider.com 7y ago

Sam Altman: People aren't worried enough about Biological Warfare

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www.npr.org 7y ago

Jury Finds Paul Manafort Guilty in Federal Tax and Bank Fraud Trial

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news.ycombinator.com 7y ago

Show HN: Plastic May Underlie the Diabetes Epidemic

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theconversation.com 7y ago

The Plastics That Surround Us May Contribute to Obesity and Diabetes

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www.medicalnewstoday.com 8y ago

Alzheimer's risk 10 times lower with herpes medication

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medium.com 8y ago

Show HN: Have we unintentionally blamed cholesterol for heart disease?

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arcdigital.media 8y ago

#RunAway from Russian-Linked Twitter Accounts That Are Posing as Ex-Democrats

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medium.com 8y ago

Show HN: Could Aging Be an Infectious Disease?

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news.ycombinator.com 8y ago

Ask HN: Who is looking for a co-founder?

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www.politico.com 8y ago

More details of General Kelly's phone hack

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thehill.com 8y ago

John Kelly's phone was breached as early as December

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nypost.com 8y ago

US warship shoots down missile during test in the Pacific

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itunes.apple.com 9y ago

Silicon Valley TV show releases working SeeFood app

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www.youtube.com 9y ago

Senate Hearing on Russian Hacking

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www.theregister.co.uk 9y ago

Dan Kaminsky Hosts SF Hackathon to Fix Internet

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vimeo.com 9y ago

Deep-Dreamed RickRoll is Nightmarish

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www.forbes.com 10y ago

Obama Seeks to Make Mark on Genetic Medicine

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www.infino.me 10y ago

Show HN: I built an AI that recognizes food

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www.infino.me 10y ago

Show HN: Visualization of Longevity and Mortality

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www.infino.me 10y ago

Show HN: Visualization of Longevity and Mortality

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Factorio 1.0 6 years ago

The world trembles as a world-class AI researcher takes an interest in a factory automation game :)

Taking huge inspiration from Folding@Home, and my teenaged fascination with SETI@Home, I threw together a prototype framework to distribute small-molecule "Docking" experiments to tackle the coronavirus epidemic.

Source code is here : https://github.com/cjmielke/quarantineAtHome

We currently have about 50 volunteers pitching in both CPU and GPU compute time, and we have already performed >100,000 docking experiments against two of the coronavirus proteins. You can see which proteins we are targetting here : https://github.com/cjmielke/quarantine-files/tree/master/rec...

Want to join the community? Windows and Mac builds are available, but you power users can jump right in with a docker image :

CPU : sudo docker run -it -e ME=<YourUserName> cjmielke/quarantine_at_home:quarantine

GPU : sudo nvidia-docker run -it -e ME=<YourUserName> cjmielke/quarantine_at_home:quarantinegpu

Ask me anything!

Nothing arrestworthy, but definitely shameful behavior of a high-ranking hospital official allegedly defrauding a large multinational company and attempting to shift blame to low-level employees that had zero involvement.

MDs no less! Forget the Hippocratic Oath!

Perhaps white-coat fraud is the equivalent of white-collar-crime in the public health world. Nothing matters more than the bottom line. Not even human lives.

Watch this to understand the problem better : https://www.unrest.film/

And this : https://www.ted.com/talks/jen_brea_what_happens_when_you_hav...

I study neurology and metabolism. If any of these patients are delusional, its an exceedingly small fraction of them. Same goes for people diagnosed with "conversion disorder", which is the idea that they are exhausted because they are dealing with some buried repressed childhood trauma.

Some psychiatrists can have a real discussion with you about the intricacies of the hypothalamus. Others ..... really not..... they will try and deal with your systemic inflammatory problems with Fruedian psychoanalysis. Worse yet is that many patients dealing with these deep fatigue and metabolism issues have been institutionalized because people think they are just faking it.

I can understand why so many chronic fatigue patients are reacting this way. My doctor once told me that during his medical training, he was taught that people claiming to be suffering from this are bonkers and must be treated as if they are psychotic.

Nowadays, the evidence is stacking up that there are metabolic, viral, and neurological factors involved, and while all of these can effect alertness, they are not ever dealt with via willpower.

The patients who have been royally insulted are the ones likely reacting this way. Whether or not the physician or scientist on the receiving end is deserving of the ridicule is case specific.

I'll add to this by saying that going on zoloft a year ago has been like the best nootropic experience of my life. In many ways, the first 6 months were like a persistent 24/7 microdose on MDMA ..... it was incredible. I also turned my life around and accomplished some of my life's most impressive work, all while not trying to kill myself anymore!

Beyond solving a massive sudden depression, it was actually quite enhancing. I felt like I was in the movie limitless. Given the pathways SSRIs target in the brain, I'd say they have similar benefits to all of that SV legacy around psychedelic use....

Sadly, things normalized and the burst of awesome tapered off. Now the medication is the new normal, and skipping doses brings the depression back, just not nearly as bad as it was. Hopefully some day we will learn how to tweak it so the immensely positive experiences last forever.

These days, I no longer think of antidepressants as any kind of crutch. If anything, it is another tool in the transhumanists toolbox allowing the human body to perform better than nature has provided.