The determinant of a polynomial mapping is a polynomial, which is the subject of the conjecture. To get the Jacobian determinant, all you need to do is compute partial derivatives of polynomials, and add, subtract, and multiply them together. All of these operations map polynomials to polynomials.
The crux of the assumption is that if a polynomial mapping is invertible everywhere (Jacobian nonzero everywhere), its Jacobian must be a constant. Why? Because the only polynomials which are zero nowhere are constants.