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sachingulaya

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For measuring survival my old lab championed the Kaplan-meier estimator for its ability to censor non-cancer causes of death. The 5yr survival can be heavily skewed if patients are dying from secondary causes such as heart attacks, getting hit by a bus, etc. Oftentimes patients with cancer have other serious comorbidities.

A used HP 5890 might be 3k usd but realistically you are looking at 40k for a refurbished unit. That's what I paid for mine. You can never turn off a GC without an elaborate shutdown procedure. They consume a lot of power and require AC to be running. You need to keep a low level of gas flowing all the time.

It's about as far from accessible as one can get. I can't even imagine sample prep and...well, it's just not a viable solution. As a manufacturing principle QC should be performed in process and at the least processed state.

I found this description of a 'typical' supercharger setup:

"The eight bay setup takes a 12kV, 750kVA feed from the utility, steps it down to 480V three phase on site, pushes that into 2000A switchgear which feeds four (one for each pair of bays) SuperCharger units at 480V/200A."

I can't comment on Hillary's character other than she seemed cold when I met her. I do have to say though that oftentimes there are larger strategic decisions to be made. "The united states has no permanent allies or enemies--only interests."

The business pitch is usually "delay evictions now". The cold caller will get a list of properties that have recently gone into foreclosure. They call and offer to delay your eviction by 3-5 months as long as you pay them $400/month. Then they have paralegals file paperwork with the courts to contest the eviction. Basically they're using due process to delay being evicted and instead of paying their landlord they're paying the cold caller. I first saw this scam being run by a group of former drug dealers.

I would complain to the state bar about your legal clinic behaving unethically. The whole thing leaves a bad taste in my mouth.

I request work samples from applicants with the same brief that would be given to a task currently facing our internal team. It makes it easy to compare candidates not only to each other but to our internal team. As our internal team has the project fresh in their mind they're aware of the requirements, scope, and limitations of the project. It makes them better able to judge the candidate's work.

Of course we pay them for this work at a predefined rate.

I was specifically referring to the brand name and I, unfortunately, can't speak to the differences with never having seen the bee pollinated honey seen in the article.

I will shed some light on THC infused honey (and edibles in general). Edibles are typically made from the lowest quality part of the plant known as 'trim'. For edibles the typical choice is ethanol for extraction which also extracts and concentrates any pesticides or sulfur used(sulfur burns are used as a pesticide alternative). Then that extract has solvent removed via rotary evaporation and that oil is mixed with honey and packaged in someone's warehouse. You'll often see honey and THC separate into two visible fractions if effort wasn't put into proper formulation.

For the honey in the article the beekeeper is hoping the trichromes(THC containing) of the marijuana plant will be carried and incorporated into the honey. I highly doubt this will work unless there are other instances of pollen products showing up in honey...but it's great marketing.

40mg of adderall daily is the maximum allowed daily amount. That makes me wonder in and of itself..I am going to go out on a limb here and say you are abusing it. Probably a lack of sleep leading to paranoia. Someone hacking your phone? It could happen. More likely is you are either having your first break from reality with bipolar disorder, schizophrenia, etc. or you are having paranoia and a mental breakdown secondary to drug abuse and lack of sleep.

Why are you taking 40mg adderall daily?

The Los Angeles Fashion District / Garment District is dying regardless of minimum wage hikes. A lot of business was from Mexico and China is going direct to Mexico these days. Also, a recent crackdown on money laundering aggravated the situation: http://www.latimes.com/local/crime/la-me-fashion-district-ra... . Unfortunately, minimum wage doesn't apply to many of these shops. They're mostly cash under the table jobs. I don't have a source for that other than knowing many, many seamstresses over the years who are now mostly out of work.

I met my co-founder and, after a 4hr conversation, decided I wanted him as a partner. We started working together within 3 weeks and its been smooth sailing for 1.5 years. We have already reached 7 figure revenue. Sometimes you meet people and you realize you are just on the same page with how you view things.

1. Don't over-estimate your ability to manage idiots--especially lazy idiots. They don't want to be managed or to improve. 2. Don't loan money to a business partner. 3. You are wrong about many things. Most importantly, you are wrong about how much people value quality vs. price. Your customer is the shopkeep--not the end user. 4. Don't hire inexperienced people. 5. Be more judicious in deciding if something is worth getting upset over. 6. Being a perfectionist will cripple your profits. Just get it done. 7. Be calculated in every decision you make. That's the only way to make money. 8. Focus on consumable goods. Sell razor blades, not razors.

[dead] 12 years ago

For context here is the original source of the quote from an NYTimes interview:

Several years ago, Paul Graham — whom everybody calls P.G. — began to film the interviews he and his partners held with prospective Y.C. inductees. When reviewing the footage, he focused on the interviews with start-ups that ultimately failed. Like any savvy marketing executive, he wanted to isolate patterns that portended ill, which he called “negative predictors.” He was already aware of a few — investors tended to be biased against older founders, for instance. “The cutoff in investors’ heads is 32,” Graham says. “After 32, they start to be a little skeptical.” And Graham knew that he had his own biases. “I can be tricked by anyone who looks like Mark Zuckerberg. There was a guy once who we funded who was terrible. I said: ‘How could he be bad? He looks like Zuckerberg!’ ”

Watching the video footage, Graham noticed another correlation: the longer he took to decide a group’s fate, the less likely the group was to succeed. “When you have to talk yourself into something, it’s a bad sign — that’s true also of relationships, hiring and so many other parts of life.” (Graham has a rhetorical talent for moving swiftly from the valley to the universal.) But after ranking every Y.C. company by its valuation, Graham discovered a more significant correlation. “You have to go far down the list to find a C.E.O. with a strong foreign accent,” Graham told me. “Alarmingly far down — like 100th place.” I asked him to clarify. “You can sound like you’re from Russia,” he said, in the voice of an evil Soviet henchman. “It’s just fine, as long as everyone can understand you.”

http://www.nytimes.com/2013/05/05/magazine/y-combinator-sili...

It's pretty easy to see how the quote wasn't received as a joke.

In regards to monthly statements...yes, I e those all the time for getting financing, accounting, proof of residency, etc. I need them. Others need them. Most web portals offer "all transactions" or "since last statement views". Just because months are arbitrary doesn't make them useless.

We are buying != we bought. I've been quoted 30% deposit and 70% due after a 6 month manufacturing lead time for heavy equipment (>250k). I'm not sure what they were buying but a lot of machines I've dealt with are made to order for application considerations. Most likely she had not purchased anything yet. If she had, deposits were probably lost.

Ugh. Got hit by this. My insurance company listed a hospital as covered. I took my daughter to the ED...then got a $400 bill in the mail for a physician we saw for 2 minutes. The rest of the visit was covered. He wasn't. Apparently all doctors who work for the hospital are covered by the insurance...but he was a visiting physician. I hate health insurance.