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rrock

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Surprising that anyone still thinks the Penrose model could work. Microtubules do not exhibit harmonic motion like violin strings. The reason is that all motion at the length scale of cells or smaller is heavily overdamped.

The environment within a cell is nonintuitive. To find out more about this, read “Life at low Reynolds number” or “Mechanics of Motor Proteins and the Cytoskeleton” by Joe Howard.

It wasn’t entirely clear in the parts that I watched, but my understanding is that slime molds are actually “social” amoeba. They often crawl around as loners, eating whatever they can find. But if they run out of food, they start sending out chemoattractants to all of their buddies in the neighborhood. They all crawl together and create a fruiting body (a spore) that eventually will break off in the wind and land somewhere else. Hopefully, in greener pastures. Those fruiting bodies are what you see in these videos. Amazing creatures, they live on the brink of multicellular eukaryotes.

Bit flips from cosmic rays. Earth’s magnetic field helps to shield us, but is disrupted now. I work with a CCD camera in a sub basement lab. On a normal day we see a stray cosmic ray every couple of minutes (as a hot pixel). On a day like today, might be every couple of seconds.

Certainly. For me it started when they removed the entire scientific stack, which broke my install scripts / brewfile. Then, they removed the ability to customize builds, which broke my emacs build. Also hit the OP issues.

In every case they were removing features that were working just fine, and in the process creating work for me. Got fed up, switched to macports (after checking out nix), and so far things are back to the way I like it.

One vote in favor of macports here. I first went from homebrew to nix. Nix was fine, the concept is great but I found the language to be difficult. Ports is closer to homebrew in its simplicity, and has a big catalog (including much of the scientific stack that was removed from homebrew).

There is no spike protein in the vaccine. There is mRNA. That mRNA needs ribosomes to make the spike protein. So think about where there are ribosomes, and where the protein is made, and you’ll find the correct answer.

I don’t know where you heard the second point, but it is equally incorrect. The mRNA encodes just the spike, with two mutations to lock it into a pre-fusion conformation. Nothing there that qualifies as a “larger stable base”. The sequence is found here: https://web.archive.org/web/20210105162941/https://mednet-co...

The vaccine produces spike protein within your deltoid muscle cells, where it is rapidly degraded and presented to your immune system. It’s not running around in your bloodstream. Unlike the virus. Which means, incidentally, that if this is a concern of yours you should definitely prefer getting the vaccine to getting an infection.

Transcription causes mutations in the spike that causes clotting issues? Do you have any idea how much transcription happens in your cells, every moment of every day? You need to reconsider where you’re getting your information.

You might have some sort of dangling config issue somewhere? I use the emacs keybindings in the Julia REPL all the time. They work fine out of the box (at least here).

Excellent advice. I'd add one more thought for the reviewers side of the equation (peer review specifically). Your objective as a reviewer is to help the authors present their case. Keeping that in mind helps to separate what additional work is essential vs. Nice to have if given unlimited time and resources. Beginning reviewers tend to lean toward the latter.

It takes training and practice to write useful reviews / critiques. Mentors should take the time to do this for their trainees.

I’m sure that Vasilevskiy didn’t pop up immediately there because he was exhausted. If his team turns it over, he’s back on his feet in an instant. No way he stays on his knees the whole game

I had the same reaction. Has he not noticed goalies playing at the top of the crease (still)? Goalies play from the standing position for as long as the can to leverage their quickness, only dropping to the butterfly when the shot is on its way or a defensive breakdown demands it. I was really surprised to see who wrote it.

Yes, and is played on a frozen soccer field, 11 on 11. No boards, the ball can go out of bounds. Scoring is much higher.

(Others may correct me, I’ve been to one bandy game my whole Life)

Optical Tweezers 6 years ago

For those interested, here is Arthur Ashkin giving what would have been his 2018 Nobel Lecture in Aspen, Colorado, in early 2019. He was unable to travel to Stockholm at the time. The talk is quite accessible if you want to understand how tweezers work.

https://youtu.be/vb58pd2ycKQ