nibs

I have $80M net worth, wife and kids and sleep on a bed on the floor. AMA.

Markets in everything: Segretation in the debt market edition.

Because the studies that looked at it didn't control for wealth.

Schizophrenia is basically symptoms of permeability of the blood brain barrier. Whole proteins pass through and mess things up. Similar to automimmune disease. Why else are those diseases on the list the only ones increasing in pravalence, and all others are decreasing (infectious, cancerous, viral, etc.). ASD is neuroprotective and tightens those cell junctions, with behavioral drawbacks. All these things are interrelated, the issue is they can be caused by 100k different contributing factors and susceptibilities.

The penjulum of "things startups are wrong about" and/or "you succeed despite this rather than because of it" open plan offices will shift back the other way in the next decade to "deep work" and "closed door productivity". Joel Spolsky & co are just two decades ahead.

Dialpad, Hubspot, Chrome, Slack, Hangouts, Tiny Scanner, Inbox, Signal.

I went through and activated Google Authenticator 2FA for everything. I am at about 45% of all accounts now. If you want to send feedback to Namecheap: feedback@namecheap.com.

Senior individual sales, full-time, in person, 2000+ person company.

[07:30]: Wake up naturally. Shower, shave, get dressed.

[08:15]: Walk 5-minutes with wife to work for breakfast.

[08:30]: Standup over breakfast with team, very boring.

[09:00]: Start working on new business outreach. Phone meetings and remote demos all morning in succession in large open space full of around 40 desks. I like the energy of the environment. I occasionally book a room if I want some space to work but mostly like the intensity.

[12:00]: Catered company lunch with buddies and/or wife

[12:30]: More work, same as before except more existing deal outreach and internal meetings in afternoon. Mostly go to a breakout space to get things done, peak energy during this time. This part is the most fun generally.

[17:30]: Walk 5 minutes home with wife. Sometimes take the long way.

[18:00]: Start and eat dinner, go for a walk again or to the gym.

[20:00]: Work on side project for 1-2 hours if time allows.

[21:30]: Read nonfiction with wife for an hour or two before bed.

[23:00]: Head to bed and hang out chatting before dozing off.

I do this everyday and would not change a thing with the exception of removing all formal training and most internal meetings and adding kids. Same as when I had a company except the part about nonfiction, side projects and standups was just grinding away instead.

Socialization is for pets. I just ran around the forest and played Runescape for my single digit formative years. I did not learn to read until I was 11. To call my childhood homeschooling would be offensive (to me), school is the whole thing I was trying to avoid. I was home though. I played sports and chess with other people my age and older. I missed nothing but the cynicical, pluralistic burnout one gets attending school. And as an adult, I would not say I am missing anything social skills wise, other than that pathological desire to be normal school people have. Mimesis begets external validation begets emptiness.

I have done a great deal of armchair research in this area. It seems like if we can figure out a way to get the salt out of the cells, Salicornia protein would be an excellent, sustainable way to offer humans a plant based protein for which the inputs are literally sun and sea water and the output is a high quality vegan protein source that can be grown in the dessert. Getting the salt out of the cells was above my head biochem wise but I hope this goes the Tesla route of disruption, starting as a garnish on fancy hipster salads and ending up the standard in staple meal cooking greens. The biggest advantage is the lack of reliable on fresh water and ability to grow on saline land. If we can create the demand the business case for a business whose main inputs are sunlight and seawater is pretty strong.

Talk to customers. Who is the customer? Talk to them. Ask them how they do it now. Ask them to describe how it would ideally work. Ask them how much they would be willing to pay, and tell them your question is not to bottom line them but to figure out how they perceive what it would be worth. Ask them if they are willing to commit to pay that if you are able to meet A, B and C minimum viable functionality. Ask them to put it in writing.

I think LinkedIn is good for information gathering, but you should ideally cold email people with an ask for 10 minutes on the phone and then schedule as many phone calls a day as you can. These are called discovery calls. Your goal is to discover what the priorities and needs of the business are in the area you intend to tackle to figure out if there is even a business there in the first place.

If those calls go well and a few people are willing to put in writing an intention to purchase it if you are able to deliver, build the A, B and C functionality as fast as possible and then call them back and ask them to pay for it. Assume half of those never actually intended to pay for it. Assume the other half will email you constantly complaining that you are missing D, E and F. Call a bunch of new people who you think might be customers and ask how critical D, E and F are.

If they are critical, ask those new customers if they would commit in writing to purchase such a solution. A few more will be willing to than before if you are on to something. Build D, E and F to appease the initial customers (they will be happy) and close the next customers. Carefully reflect on what the potential market is now that you have ABCDEF. Try as much as possible to sell that to new customers until you have a critical mass. At that point you should be nearing product/market fit.

Then ask yourself what you are best at? Try to use customer money to fund hiring everything that is not that thing. Continue to repeat this process through increasingly large and complex markets and layers of abstration below you in the organization heirarchy. Sorry I only have time to write but not to edit, hope this helps.

Include a line about using their likelness for marketing purposes in the terms of service and contract and agree to waive it for anyone not comfortable with the concept.

All my friends, immediate and extended family communicate over Signal. <50% use Facebook, login once a week and are horrified by the posts, log back out. We are probably not typical users of technology, but Signal is our core communication tool now.

Waterloo, Ontario, Canada.

It is insane, and yes you can "expense" mortgage interest against your taxes, and in the case of a rental, a portion of everything else too. Incentivizes owning houses.

Celiac here. I went through a not nearly as bad although still 18 month long painful regression, diagnoses and recovery period before getting to my current better than ever state (thanks to diagnoses and fixing my diet). My brother and I wrote a learning algorithm in Go that allows you to log your food and how it made you feel, and then it evaluates that against all of the other things you have eaten and changes the score for that food. After a month or two of data you start to see compelling patterns, and it allows you to isolate single ingredients through continued trial and error. If something results in 10 bad experiences and no good ones, it is probably a trigger food and should be eliminated. On the opposite end, you can conclusively rule out foods by trialing them with a bunch of other ingredients and seeing if they cause problems.

I built it because three people I know went through processes similar to the one you describe and they found the trying foods process very hard to track in a way that made is easy to determine which foods were a problem. I never took it further but the Go app is deployable and I think there is a great service to be built I have just been busy with my day job. I think that if this job goes well I will have enough money to work on this mission full time and at that point I will revisit this project and try to make it more functional and integrate with other medical and health devices and APIs for easier logging and better correlations (ie. eat a food, that increases heart rate 10-20bpm indicating autoimmune response of some kind, that is automatically tracked and the food is scored lower).

I signed up on the website, first name starts with R and time around 21:20, feel free to email me and we can chat.

It would be easier to make people give up most of their rights and freedoms than it would be to make them stop eating bad food that will make them an expensive burden to the healthcare system. The only solution is to regulate and tax the way cigarettes are. All that Pepsi goes to fund all that diabetes and heart disease. Everyone, including the highly competent managers and researchers at Pepsi, knows it is bad for you. That does not mean no one should work for Philip Morris - it just means there are probably more virtuous ways to spend your time. Ultimately, society will give the people what they want, so we should tax the bad wants.

This makes sense. In business, it pays to be objective. But this effect is a coping mechanism that spans areas of life well beyond business. Similar to how everyone considers themselves an above average driver - narcissism/inflated sense of self keeps people in the gene pool. It is not a long term strategy, though, so the longer you lie to yourself, the more life will find your real level for you. I think that you can actually go a long time with this reality distortion - and the same narcissism can be implicated as much in success as in failure.

What about using m.uber.com with a browser that sandboxes location data requests effectively?

Submitted: https://news.ycombinator.com/item?id=13060655

PatronScan[1], no, no. https://www.patronscan.com/id-scanner-for-bars/

This already exists. My parents own a bar and were pitched a technology that would instantly screen problem patrons from a cloud-based data store. Further it can "remember" problem patrons if you flag them on your internal cameras and then use that to prevent them from entering in the future. It currently has many customers in the US.

I think that rich countries are having their social benefits priced into houses.

Where I am (Canada), house prices in some major metro areas fairly closely follow what school district you are in. So we have "high quality public education" which you then pay for in mortgage interest and principal instead of tuition. This (mostly) still results in people getting what they pay for, but it also leads to strange distortions.

The more the world becomes globalized, the more people will start pricing the social benefits of a location into the cost of living, simply by going there and driving up demand.

Eventually a given government social program dependent will be commoditized to the extent that you can work in a high cost of living centre but with the exact same quality of life as you would in the equivalent low cost of living centre. Just with less zeros on your income and bills.

The video makes a great point about how people want a net benefit to the curb appeal of a given area, but it is also an issue of pricing things into housing that used to be priced into the products themselves.

If it is early on, do a needs analysis call separately from the demo by a week or so. In that time and if the lead qualifies as worthwhile (adding 1+ months to runway), build whatever extra feature or screen they mentioned needing but you know you do not offer. Or three if such is the case. And then give them something that meets their need 100% during the demo and try to close them then.

Yes. And yes but not instantly. More like over the course of an hour or two. It would not be possible to get to that speed without performance tires in the first place, so the assumption would be that it would work for a time. Good luck parallel parking or driving over bumps though.

I spent a day battling with getting a custom ROM on my Redmi 3 and gave up. In case anyone reads this: Xioami make amazing phones for the price. This $120 USD phone outperforms my S3. But getting a custom ROM on a Xioami is getting increasingly difficult - you have to ask for permission, jump through hoops to unlock the phone and sometimes it just does not work. Xioami is the Apple of China - great UI but increasingly closed ecosystem. Their OS is called MIUI, which is basically Android with more customization options (necessary for the markets they serve). It is a great phone and OS, but it is more complex than just flashing CyanogenMod (unfortunately).

I would never hire someone back who accepted and then bailed on a job offer. I would hire someone back who rejected a job offer and got back in touch at a later time saying circumstances have changed. I think once you make a commitment to someone that you will do something, and then you do not do it, regardless of the legal repercussions most people will not want to hire you as a result.

It is possible that you are amazing at what you do and that they will bend over backwards to make a spot for you even if you abuse them. I suspect however the good advice for 90% of people asking that question is only take the start-up job if you never want to work for Facebook or the person who offered you the Facebook job.

The knee-jerk outrage and intolerance for people who disagree with you.

1. Systemic yeast infections are caused by gut dysbiosis. Gut dysbiosis is basically overgrowth of bad bacteria.

2. Migranes, bloating, brain fog, thrush all over body, bowel transit issues (too fast or slow), anxious

There is a medication that is sold OTC called Diflucan. It is magical if you have this problem. The only long term fix is stop eating food that makes the cell walls of your bowels disintegrate. The goal is for large proteins to remain in your intestines and not leak into your body and cause your immune system to attack itself.

Part of what leaks out is yeast cells that can infect different parts of your body. Candida is a bad Google term to use, because of the magical voodoo associations, but gut dysbiosis is well studied and found often in the immunocompromised (ie. AIDS patients).

More common than AIDS is that it is a chronic food allergy that goes undiagnosed for years and leaks to deterioration of the quality and accuracy of the immune response, paired with the leaking of proteins out of your gut. All fairly new science too so doctors still consider it voodoo.

Some foods make your gut leaky (alcohol, egg whites, sugar) and some cause the problems when they leak out (gliadin, casein, yeast). It is very complex if you rabbit hole it. In general it falls under neuroimmunology.

Google "Psychoneuroimmunology" for the mental health implications and "Neuroimmunology" for the broader physical ones.