HN user

jtmcmc

571 karma
Posts1
Comments324
View on HN

This is definitely a take that ignores the massive amount of utility for ML that exists outside of generative images and NLP on the one hand and on the other vastly misrepresents the time it takes to understand a model, assuming one does not already have a background in CS, linear algebra and in particular matrix calculus, probability, stats, etc...

at the lower level - detecting senders trying to send spam is a big one as well as detecting sending / deliverability problems

I'm not familiar with what mailchimp is actually doing with their marketing automation / analytics stuff but you could use "AI" ( or basically statistics in this case ) to analyze the resultant data.

There is some good modern medicine, but the fixation on genes handicaps certain investigators. This isn't medicine - this is science. This isn't the development of a treatment but an attempt to understand biology.

Genes are useful because they are far more fixed and they are far easier to measure than many other things that could be measured.

"I think they’re trying to say “it’s not the mother’s fault the kid just has bad genes.”

They're saying non genetically inherited material, such as mRNA or proteins, from the mother was shown to have little impact in their study.

In the real world there are non-genetic causes behind almost all of the symptomatic presentations of children medically-cursed with the diagnosis of “Autistic”.

The causal nature of any complex biological state such as ASD is almost always varied and emergent from many sources and attempting to understand them is useful. It is especially useful to look at genetics because it is (relatively) cheap to get a person's genetics and painless - whereas studying the microbiome is much more difficult and expensive. even the review paper you link to - which has precious little actual research on autism and the microbiome stating

And in autism spectrum disorders (ASD), there are hints that the gut microbiome may play a role. Studies of fecal DNA extracts have found Clostridium or Desulfovibrio clusters over-represented in children with gastrointestinal complaints and ASD as compared to children with similar GI complaints but typical neuro-behavioral development32–34. Furthermore, clinical improvement has been reported anecdotally in children with ASD who develop fever35, receive oral antibiotics36, or ingest probiotics37, all of which are likely to alter the gut microflora. While these initial studies are promising, they suffer from small sample sizes, in part due to the laborious, conventional, culture-dependent techniques used to identify bacterial species

this is not just synthesizing a chemical - this is using an engineered virus to deliver a newly functional gene.

There is a reality here that these therapies are really fucking expensive to produce. If we want them to be cheap or free their discovery needs to be subsidized and funded in a non-profit driven manner