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imoldfella

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Availability: no gatekeepers. methylene blue predates the FDA and is grandfathered. Unless you want to break the law, it will be hard to biohack with rasagiline or moclobemide. Also probably some safety in using something that's been used long enough to be grandfathered.

It's benign in the tested environment. You can't really test every possible environment (diet, climate, etc), so it seems roughly comparable to the halting problem; Does there exist a micro-deletion that in some environment causes this life to halt? It's unsolvable at DNA scale.

100% agree. If starting now I think you should consider targeting mlir[1]. It fixes many problems you will have with llvm, and allows you to create language specific dialects and transformations. Impressive new work by a top-notch team led by LLVM creator Chris Lattner. It has LLVM as an optional target, so you get that for free.

For a parser, you should consider using tree-sitter[2]. Tree-sitter gives you live editor support for free. Impressive work by Max Brunsfeld.

[1] https://www.youtube.com/watch?v=qzljG6DKgic [2] https://www.youtube.com/watch?v=a1rC79DHpmY

Go to church, what have you got to lose? With all its problems every church is filled with nice people and I guarantee with a few calls (probably 1) you will find someone that will pick you up and take you. No matter how rural you are, there is a church close by.

The Exercise Pill 9 years ago

That certainly sounds more credible. I encourage all the HN'ers north of 40 to try weightlifting. We have members older than myself seeing good results.

The Exercise Pill 9 years ago

No, I _started_ lifting seriously at 48. I was objecting to the observation that loss of muscle was inevitable after 40 "even the athletic". Its not. That doesn't address the value or danger of GW501516 since I didn't use.

Most of the people using this drug are using it with more serious exercise than I'm doing. In practice its being used as an exercise supplement, not replacement.

The Exercise Pill 9 years ago

"After the age of forty, all of us, even the athletic, lose about eight per cent of our muscle mass each decade, with a further fifteen-per-cent decline between the ages of seventy and eighty. "

This has not been my experience. I have added pretty substantial muscle mass between the ages of 48 and 55 with fairly conventional weight lifting and diet with no PED's. My back squat has gone from 185 to 385 (pounds)and my deadlift from 265 to 465. 40 seems way too early to start packing it in.

Another reason for Small Investors to stay away is the senseless tax hassle. I didn't invest because I had any ambition to get wealthy, I just wanted to "give back" and help some ambitious young entrepreneurs get started. Now I'm filing complicated tax forms for money I'll never see because those young companies made 10$ in interest from the money sitting in a bank.

My understanding was that the replica would go down in order to recover the failed server. This was a side effect of the way snapshots and command logging worked. You couldn't just restore the snapshot on the failed node because the multipartition commands would have to execute against the entire replica. Instead you would restore the snapshot on every node, and roll forward the entire replica.

The Spanner design seems more resilient in the face of server failures. The initial Calvin papers call for taking the entire replica offline if a single server in the replica fails. Are there more advanced versions of Calvin that get around this?

Did you consider libuv? If so why asio over libuv. I've never taken time to benchmark them, but I have built web servers on both. Libuv has broader api support like cross platform file aio. Asio has more convenient c++ bindings, but there are some third party bindings that I haven't tried.