HN user
can you, or someone who understands this, explain to the layperson what this means.
the last sentence in particular, what does reinfection have to do with error correction (what is error correction (assuming it has to do with the genome)?)
why is that an advantage over influenza?
do you have a link to this solution
why was this flagged? i would be interested to hear the perspective of the HN userbase on this event / issue?
what are the three you are thinking of?
USA
China
Russia
and their respective allies / blocs ?
"It is my perception that, at least in America and I suspect in many other places, competition pressure centered around places with strong "second place" (Job) opportunities combined with decades of civic mal-planning and treating symptoms (for some) rather than root causes (for all) have combined with a regressive tax/compensation structures to destroy the middle class and upward mobility. "
i literally cannot parse this sentence. i tried - i am a native english speaker but it's just confusing to me what the proposition being made here is. i tried reading it a few times.
it is late but if someone could clarify it would be much appreciated.
why did this get downvoted, my first thought was exactly along these lines. does anyone have an answer?
Ever since practicing mindfulness and become more aware of my emotional state, drinking alcohol has become a nonstarter for me. It took a while for me to truly connect the dots, but, following a night of imbibing, I crash really hard on not just a physiological level but an emotional, psychological level as well. In fact I find it hard to separate the two reactions. To me they are basically the same thing, overall increased levels of "pain" or "anxiety" or "neurosis" manifesting in my inner being, my soul if you will.
I know that sounds a bit woo woo but it's sort of an ineffable and inarticulable idea. I'm 100% sure I feel it though, every time I drink I sleep poorly, I'm much more irritable once the alcohol wears off the next afternoon, and by the time the evening comes around, assuming I don't re-dose, I'm much more prone to ruminate on negative thoughts or seek mindless stimulation to distract my mind from the general malaise.
I think alcohol really is a mainstream and socially acceptable means of anxiety self-medication. It's a deeply engrained cultural habit that has been around for millenia, and I don't expect or advocate for it to stop, but for me it has palpable deleterious effects on my whole being.
what brand / dose do you drink? looking to switch off coffee to something more benign
I don't hold any bitcoin or cryptocurrency and am a crypto skeptic in general but isn't this argument commonly rebutted with the comparison to gold, to which all of the same criticisms apply but which has nonetheless maintained value for millenia?
how would you reword it?
It's all anecdotal, but:
When I was an adolescent I was diagnosed with ADD after a few days of examination, and was recommended adderall, which my pareents thankfully refused.
My mom told her GP she had trouble focusing and was prescribed adderall pretty much willy nilly.
I know quite a few people who are perpetually on SSRIs for anxiety or depression, yes it works as a palliative measure for some but I do question both the long term efficacy, if the magnitude of the side effect and dependence risks are understated, and most importantly whether or not the patients worked hard at all of the endogenous variables relating to their lifestyle to optimize for happiness before slavishly accepting their diagnosis.
I don't like that the conspiracy nut / tinfoil hat / anti science pejorative gets thrown around so easily as an argument ender in discussions like this. It is most definitely NOT scientific how these diagnoses are done, it's heuristic based, it's based on observed models and patterns, obviously, since we barely have slightest idea about how our brain is working under the hood / how it differs among individuals / what leads to long term convalescence.
So, for some people, diet, exercise, getting out of unproductive or toxic relationships/jobs, can help, for others, they need the boost of an SSRI or something to get out of the bog, etc. but I definitely suspect that very many people are prematurely getting pushed to the latter option without fully exploring the former, as was the case with my mother and I (except with focus issues instead of depression, though i suspect they're related)
Think of the parent commenter -- Say he went to a doctor or a psychiatrist with his issues. How much time do you think they would spend with him before getting to the point of prescribing him something to take care of his issues. Maybe 10 hours max? Probably more like 2 or 3? Often times less? Whereas he is obviously a thoughtful, intelligent, and diligent person who has probably spent years responsibly experimenting on what works for him and found that it is marijuana. Yet that would never even be an option for the docs to prescribe to him. So if he were to slavishly follow what you deem as "science", he would be stuck in the paradigm that he needs an SSRI or benzo or whatever it may be. Whereas by being anti-scientific, and self-medicating, he's here telling us how happy/successful he is.
Another more prominent example would be the opioid crisis.
A lot of people seem to be willing to kowtow to the current dogma of the medical / psychiatric community with regards to mental illnesses (depression, ADHD, etc.) Once you categorize these things as objective "chemical imbalances / medical issues", the next logical step is to treat these with "medicine", like Prozac or other SSRIs, or amphetamines in the case of ADD.
Many people don't seem to have the same respect for self medication, however. I personally think trying alternative treatment options, be it drug based or experience based, is always a better option than slavishly following your doctor who himself is often slavishly following some established medical dogma du jour or his own financial incentives. That is not to say that standard medication is not effective in some or many cases, moreso that there are very many people who think they "need their medicine" because a doctor or psychiatrist has diagnosed them with something that is at best an educated guess (with high error margin) along a multidimensional space of possible psychological profiles that we don't fully understand. My point is that by breaking down psychological issues into various abstract "disorders", it makes questioning a Prozac users choices tantamount to begrudging a diabetic for taking his insulin.
can someone ELI5 this? I am a former SW engineer, but havent read through code in a couple of years, so it can be a technical explanation. I just don't understand what is different about this than regular functions as first class citizens? I tried to get it but maybe there is an easier explanation for laymen-ish people.
what does 3LA mean?
Can you (or some other knowledgeable person) explain the mechanics behind this. I've heard it a bunch of times and looked into it but I can't fully grok the advantage (and magnitude of the advantage) of being the global reserve currency
Same here! Glad other people felt this way.
Can someone who understands the mechanics of this ELI5 how this works?
so the parent is a UK citizen but can't pass his citizenship on to his children? And his future wife is a taiwanese citizeen, but because he would have to enlist in the taiwanese army to become a citizen, they cannot raise their family there? Can someone flesh out the details for the clueless and unworldly like myself?
What part do each of these things play in the parent posters predicament vis a vis starting a family:
a) Being born in Switzerland b) Parents being British c) Parents being French residents d) Girlfriend being Taiwanese e) Mandatory Taiwanese Conscription Laws
What UK law prevents parent from marrying his GF and raise his children in the UK? Why can't he live in Taiwan as an expat and not join the army?
presumably for time to detect and prevent fraud or illegal transactions.
what about product placement, PR in print media, "native" or content ads. to say nothing of social media "influencers"
Isn't India English speaking? And HN has a huge Indian demographic I would imagine.
And historically, I believe they have been allied with the Soviet Union whilst the USA has historically allied with their arch-rival Pakistan.
But Hitler truly was great at building relationships with the German people. Depending on the context you can interpret that as spin but to me it is also a factual statement, to rise to power from relative obscurity at that level requires being excellent at the art of social skills / climbing, aka politics.
Why are you using 1% of GDP for your number?
2018 spending will be 4 trillion
2018 GDP is 20 trillion
so a thats a 5% increase
What's the difference functionally between a tax on your competition (all except you) and a subsidy for yourself?
Do bars really sell well liquor at a loss? I've never heard that and I can't imagine that being true just from my experience as a customer in bars.
Even if a Rum & Coke is 5 dollars (I'm used to it being more around 8-10$ on average, but being conservative), the unit economics still seem extremely profitable to me. I would think the coke from the fountain costs pennies, and the shot of (well) rum would be max one dollar.
what supplements, if you dont mind me asking? what what use? (if they are a medical condition and not health or "nootropic" feel free not to say)
This isn't fair, the OP broke down his arguments for why the author was wrong, and all you do is appeal to the author's authority as a "trained professional". After a certain amount of life experience you realize that "trained professionals" in some (many?) fields of study often have glaring gaps in their knowledge of are purposely ignorant of some set of facts/ideas that do not corroborate their philosophical leanings.
Either way I feel it would have been more productive to rebut the GP on the merits of his arguments. For the record, I agree with him, though I am also not a "trained professional", just an amateur who has spent a lot of time thinking about this subject.
Why do you go down mil(lileter?) nicotine as you progress? pardon my ignorance i have only vaped a few times.
Why did your jaw hit the floor for JUUL?
whats bfe??
I've noticed this type of comment a lot on HN lately. An innocuous comment which features the tiniest sliver of an attack surface, in this case use of the pronoun "she" in an anecdote, is used as a launchpad for a completely unrelated implication or outright accusation of prejudice or ignorance.
When I read the grandparent comment and saw the (uncommon) use of the female pronoun in the story describing a negative action, I instantly thought of this type of response. I'll admit it, I even had the impulse to make a throwaway and troll and say something like the parent comment just to see the reaction. (I figured it would be swiftly downvoted/greyed).
Despite my own impulse to troll, I truly can't tell if this comment, and others like it which are not hard to find here, are performance art of the reductio ad absurdum kind, a sort of Andy Kaufman-esque "triggered SJW" act, or if this ascribing of every phenomenon to some type of systemic inequity no matter how farcical is a real part of the zeitgeist now.
I'll admit my bias: I'm tired of oversensitivity and bucketing everything into these overly broad categories of discrimination. I like to be able to use whatever (third-person) pronouns I want in my stories, etc. However, I have always thought that the "triggered overreeacting SJW" archetype was mainly a boogeyman created by immature people at the opposite of the spectrum, the type who frequent r/theDonald or breitbart or what have you.
After seeing these types of comments here so consistently, however, I cannot be sure!
Quora has become an absolute cess-pool of thinly veiled content marketing / spam and pseudo-intellectual self-help Ted-talky BS, in my experience at least.
When it was first out there were a lot of smart writers posting thought-provoking content, a lot of (SV) insiders giving interesting anecdata, etc. It seems that it has devolved into a more yahoo answers meets TED / stevepavlina.com type community now, but maybe that's just my feed. I admit that I've hardly used it in the past few years so it could just be my shitty and uncurated list of topics and people i follow