graaben

I'm lucky to be able to see it from my apartment living room window, and even after 3 years it never gets old!

My wife (early 30s) was recently diagnosed with thyroid cancer and it's been absolutely shocking to hear how many other young women just in our social circle have also had it.

Honest question - if no one is going to change their life, shouldn't we then be focusing on creating a future where they don't have to change? If you gave people a choice between paying higher taxes to achieve abundant clean energy, carbon sequestration, new biodegradable packaging etc. or fundamentally changing life as we know it to slow down emissions, which is more likely to happen?

Is it naive to think we could prevent the impending ecological collapse and international conflict with mass fusion power? Unlimited energy to remove carbon from the atmosphere, oceans, etc. You also don't need to sell the rich on a life of austerity, as that kind of electricity would allow us to continue and even increase our current Western way of life.

Here in LA the fad seems to have ended around the start of covid in 2020. I used to see dozens of people a day riding them and now I rarely see any, and if I do it's usually a personal scooter not rented from Bird, Lime, etc. I still see scooters from those companies clogging up the sidewalk, I just never see anyone actually ridings them.

I believe they are forecasting a loss of another 2mm subscribers in Q2.

Similar story to where my wife went to high school, just outside NYC but on the other side of the Hudson. Multiple kids diagnosed with cancer shortly after high school, including one that died of a very rare form. My wife herself was just recently diagnosed with thyroid cancer 15 years later.

https://www.huffpost.com/entry/sudden-death-whats-in-the_n_1...

I'm not even talking about mass-affordable, I just mean being able to buy a home on less than a $600k/yr income. Do wages and housing prices continue to grow at 20% YoY indefinitely in cities like this, eventually pricing out everyone except the ultra high net worth?

My assumption is that a large percentage of the people who fled NYC/SF in March 2020 are either 1) going to miss the city once it fully reopens and they remember why they lived there in the first place; or 2) their "remote forever" job is actually going to become hybrid and they won't want the 2 hour commute.

I haven't really seen much written on this (maybe I'm just not looking) but what does the future look like when only the top 10-20% can afford a home? Do 80% of families rent forever with no real possibility of being able to buy a home near an economic center? What does that look like for the broader society when so much of the American dream and self-worth is built on being a homeowner?

I live in LA and I think about this a lot when I see the only homes for sale here going for $3-4+ million. How much longer can this continue?

Do you expect things to get better in the future? I'm not in the market to buy right now, but I'm trying to understand if the current situation is the new normal or still a reaction to covid upheavals. My gut tells me that in 2-3 years things will be much closer to normal as rates rise and people that fled to suburbs decide to move back to the city.

How did you go about finding a farm to buy from? I'm very interested in doing this.

What would you say a good dose is for San Pedro? Have you ever tried a higher dose?

I had a similar reaction after reading this book. I spent a good part of 2020 and 2021 in a deep dive of learning about psychedelic culture, science, and cultivation/synthesis. Regardless of how the science relating to mental health develops, I think these substances are crucial tools of personal exploration and should me more widely (and responsibly) used.

"The Hospital" by Brian Alexander

This book changed my thinking on so many different topics - the US healthcare economy, the rise of Trumpism, and the erosion of the industrial Mid-West. This book really opened by eyes to those communities that have never recovered from the Great Recession and explains so much of what we have seen politically since 2016, including the current left-right Covid split. Highly recommend for anyone who wants to get even more angry at the current state of our healthcare system.

Can you elaborate on this? I've watched that interview and didn't get the sense that anyone was "tired" of Pollan. Hamilton is an expert and maybe was able to bring the conversation away from some Pollan's talking points, but I would say the drug community is overall mostly grateful for the discourse he's fostering.

This has been almost my exact same discovery path but I'm a few paces behind you. I would also highly recommend Carl Hart's "Drug Use for Grownups".

I understand what you are getting at, but the issue is a lot more nuanced than that. What about a substance like LSD which has no known LD50 and has been proven to be less harmful than other "natural" drugs like alcohol and tobacco? At what point are heroin and cocaine no longer considered plant-derived?

In my opinion the only real solution is full legalization with better education and addiction management.

Ad arbitrage - essentially buy a click on Taboola for $0.20 and send the user to your sham website that displays ads from a separate network (Ad sense, Facebook, or one of the seedier options) and hope you get that user to click an ad that pays you $0.22. Make a little bit of money while making the world a little bit worse.

Any idea if another backend bank will pick up these accounts? Would be much easier to stay with Azlo while they sort out their banking partner vs having to completely transition everything.

If anyone is interested in this topic, I'd highly recommend reading the Book of Woe [0]. Mental health diagnoses have been based on the DSM for nearly 75 years, however it's an extremely flawed book to say the least. The creation of each version has also been a very contentious and political process, leading to major influence from pharmaceutical companies and others with financial motives.

The problem with mental health diagnostics though is that there really is no good alternative yet, so for the foreseeable future we will be making huge, life altering decisions for people based on what is essentially a subjective judgement call.

[0]https://www.penguinrandomhouse.com/books/310517/the-book-of-...

I was shocked when I found out that the current most effective therapy modality, Cognitive Behavioral Therapy, is only successful in 50% of patients.

I'm very hopeful for the future of psychedelic therapy, as it seems to be very effective after just a single dose and non-toxic.

Innovation in the mental health care space. Right now most of the top funded startups are working on either 1) Simplifying access for wealth people to the already available supply of therapists; or 2) Removing the human component entirely by creating with apps which have very little evidence to back them up.

I see mental health care as one of the most important problems of out time, at the root of so many of the issues we see in society today. Yet government has been very slow to act, which in turn means insurance companies don't modernize their reimbursement policies, which then stifles innovation.

I keep reading about how the long term play to justify the valuation is moving to last-mile delivery of retail, pharmacy etc. But there is a reason that Amazon distributes out of a central warehouse - it's much more efficient than sending individual drivers to a bunch of Walgreens around the city to pick up prescriptions.

What I just can't understand about companies like DoorDash, Uber Eats etc. is that it seems to be a lose-lose-lose proposition. It's more expensive for the consumer with restaurants often raising prices and delivery fees etc; the restaurants make less money per order; and the delivery drivers are often making less than minimum wage and rapidly depreciating their cars. And on top of that, these companies themselves are mostly unprofitable!

So who is benefiting here? Where is the true value for society being created? Yes I can get any restaurant meal delivered to my home in 30-45 min, but is that one small benefit really enough to sustain a $60bn market cap?

I spent some time in a fairly well known startup incubator. What always stood out to me is that the other founders in the program seemed to be more interested in playing the part of a "startup founder" than they did in actually building their companies. They would hold hours and hours of coffee meetings, pitch deck reviews, and presentations, but spend very little time each day actually coding or making sales calls.

I think a lot of this hustle culture comes down to wanting to feel productive, but at the same time wanting to avoid the difficult problems that come along with being an entrepreneur. It's a lot easier to talk about how hard you are working than to actually do the work itself.

I know your goal isn't to actually browse the site but you can get around the sign up modal by adding ?hide_login_modal=true to the URL

Not only the fees, but also just a completely substandard final product. Every time I have used one of these services (pretty much only when I get a promo code) it arrives late and cold. I would be furious if I spent an extra $5-10 on my meal for that to happen.

On a side note, I've noticed that most restaurants around me will add $3-4 per dish when using Uber Eats vs. just calling them directly.

Any time money is involved I have to believe there will always be a motive, however small, to alter results for financial benefit. It's common for other "trusted" media companies to be impacted by their advertisers - why would the NYT be immune?

I used to work for on of those "review" websites and it completely ruined my trust in most online product review sites. It's all just affiliate links, optimized for which offer pays out the highest conversion fee, with little to zero regard for the actual product.

I would pay a decent amount of money for a tool that just filtered out any sites in Google search that promote products using affiliate links.