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go_prodev

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Streatham High Road still seems like a grey area that should be considered a high street.

It probably was a road (connecting 2 towns with no houses) when it was first named, but is more of a street (with housing either side) now, and is definitely the primary commercial street in Streatham.

As someone who always prefers native SQL over ORM queries, I'll add a couple of counterpoints.

Most IDEs provide intellisense/validation of ORM entities, vs treating SQL like a raw string.

ORM entities also make refactoring and impact analysis slightly easier.

Despite those benefits, I generally find ORMs a pain for anything besides the most basic queries.

Glad to see it mentioned here. I used it a few years ago and it worked really well.

It makes it especially easy to drag and drop file copies across computers.

Sorry I meant setting up an account in the FB ecosystem. Prior to that I didn't use FB, WhatsApp or Instagram.

WhatsApp is that middle ground in some parts of the world.

Upon moving to Europe we discovered that WhatsApp is the preferred way to connect with friends, employees, social groups and schools. It was actually the driving factor in me conceding and setting up a FB account.

That sounds really interesting.

Out of curiosity, how do you use Node for this purpose? Is it building a real time dashboard?

My company has possibly similar challenges. We have lots of sensors on equipment that streams information every few ms through a time series database from the vendor. It's used to build monitoring dashboards, trigger alarms and help engineers to prioritize and optimize equipment settings, and look for trends over time.

It's such high volumes that capturing it and analyzing can be difficult, so we use a combination of vendor systems, Azure Synapse and Power BI. There are still lots of opportunities to improve, and I'd be interested to hear how you landed on your setup and what you do with the data.

Phone.wtf 3 years ago

I rarely get calls, so when I do, I usually don't notice it ringing in my pocket.

I'd prefer a phone that zapped me.

It appears to be a pretty active area of research on Google Scholar, which is where I first learned about Cyclodextrin for heart disease.

Here are some of the links I've read recently, which sound promising to me (a non-expert in this field).

Microarray patches to deal with bio-availability of Cyclodextrin: https://www.sciencedirect.com/science/article/pii/S014486172...

Cholrem company has a commercial product Cavadex, which they claim can reverse arterial plaque: https://www.cholrem.com/

Cyclarity Therapeutics have a Cyclodextrin candidate drug they are hoping to start trials on next year: https://cyclaritytx.com/our-science/

Cyclarity (formerly Underdog Pharmaceuticals) published an article on their technology to use Cyclodextrin molecules to encapsulate "toxic biomolecules" including 7-ketocholesterol which they believe is linked to atherosclerosis and macular degeneration. I think this might be the approach they are using with their candidate drug linked above. https://www.sciencedirect.com/science/article/pii/S037851732...

I get the impression that Cyclodextrins are far from perfect, but at least there is some hope for non-invasive treatments in future.

Normally EXCEPT or MINUS does a good enough job.

For full comparisons of MSSQL tables, I often use Visual Studio which has a Data Comparison tool that shows identical rows and differences between source and target.

If it helps to put your mind at ease, in some parts of Australia Kangaroos are a pest. They are culled in agricultural areas and this treatment prevents some of the animal from going to waste. They're also often roadkill as they chase headlights at night.

Companies pay hunters around $1-$2 per kg for the kangaroo meat. An adult kangaroo can be upwards of 60kg (130lb). The meat is often used for dog food, but is extremely lean but a bit gamey tasting I've been told.

So, hopefully this treatment doesn't cause additional death of the roos, but helps to make their deaths less wasteful.

Years ago I bought my dad an Audible subscription, but because it was a gift I signed up with my email address and then changed it to my dad's address on his birthday. Somehow I ended up inside his Amazon account because I used his email address. I guess some of the backend logic is hard to get right the first time.

Another time I was talking to a credit union CTO who was dealing with someone blocking other people's account access by picking a random account number and making 3 bogus guesses to lock them out. At the time the credit union had a policy that required calling them to unblock... which was a PITA on weekends when people need money.

Battery life gets mentioned quite often with laptops, but is it still really that important?

I run my business from an X1 Carbon, but it's more about portability than battery life. Trains, planes, Starbucks all have power available so it's constantly plugged in and I can't remember the last time I used it on battery for more than an hour.