HN user

folli

3,847 karma

Bioinformatics and Data Science.

Working on CubeTrek.com in my spare time.

github.com/r-follador

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github.com 3mo ago

Show HN: Gemma 4 based local RAG on 25 Years of news articles

folli
1pts0
github.com 3mo ago

Show HN: Local RAG on 25 Years of Teletext News

folli
2pts0
github.com 6mo ago

Show HN: TeletextSignals – Local RAG over 25 Years of Swiss Teletext News

folli
1pts0
github.com 1y ago

Show HN: High-resolution surface analysis with Lidar data

folli
66pts10
github.com 1y ago

Show HN: 3D Terrain simulation for hiking, skiing etc.

folli
150pts62
decodinggenomes.org 2y ago

Decoding Genomes: Uncovering Evolution and Population Dynamics

folli
1pts0
cubetrek.com 2y ago

Topographical 3D models from GPS tracks

folli
1pts1
community.wolfram.com 2y ago

Ancient Plagiarism? An Analysis of Claudius Ptolemy's Star Catalog

folli
1pts0
news.ycombinator.com 2y ago

Ask HN: Can you recommend me an email marketing service?

folli
2pts1
liambai.com 2y ago

How to Represent a Protein Sequence

folli
1pts0
old.reddit.com 2y ago

An Open Source Alternative to Strava

folli
14pts2
www.nature.com 2y ago

Medical AI could be 'dangerous' for poorer nations, WHO warns

folli
4pts0
www.science.org 2y ago

Evidence linking Epstein-Barr virus and Multiple Sclerosis is getting stronger

folli
25pts1
github.com 2y ago

Show HN: I'm building a Strava alternative (GPS tracks visualizer and analysis)

folli
2pts1
news.ycombinator.com 2y ago

Ask HN: Those making $500/month on side projects in 2023 – Show and tell

folli
129pts77
andywoodruff.com 2y ago

Solar Eclipse 2024

folli
5pts0
cubetrek.com 2y ago

Show HN: Cubetrek – a Strava without the social crap

folli
4pts4
cubetrek.com 3y ago

Show HN: Google's photorealistic 3D tiles for GPS activity visualization

folli
2pts1
sp.reddit.com 3y ago

Reddit's Logo Archive

folli
2pts0
cubetrek.com 3y ago

Show HN: I'm building a Strava alternative without all the social media crap

folli
16pts8
cubetrek.com 3y ago

Show HN: Create your activity heatmap from GPS files

folli
2pts0
cubetrek.com 3y ago

Online 3D Viewer for GPS Tracks

folli
1pts1
www.youtube.com 3y ago

Tetris, Movie Trailer

folli
2pts0
cubetrek.com 3y ago

Beta Testers wanted for my 3D GPS track visualizer

folli
1pts1
github.com 3y ago

Day and Night Map for Android is now open source

folli
2pts0
github.com 3y ago

Nuftu is now open source

folli
1pts1
github.com 3y ago

GeneWarrior is now open source

folli
3pts0
cubetrek.com 3y ago

CubeTrek (a Strava alternative) is in public Beta

folli
1pts0
news.ycombinator.com 3y ago

Ask HN: Those making $500/month on side projects in 2022 – Show and tell

folli
135pts70
cubetrek.com 3y ago

Show HN: Topographic 3D Track Visualizer

folli
1pts0

Also, depending on the ingredient, it makes more sense to use cups as a measurement of volume, not mass, when converting to metric. E.g. liquids, yoghurt etc.

Another thing: although not strictly metric, but European recipes also use tablespoon and teaspoon as measurements for smaller volumes, so no need to convert this.

Just my two cents, other than that very nice work!!

This argument is not limited to gene therapies, but would apply to pretty much every pharmaceutical product.

One issue is however that the actual costs are not so much in early R&D (what the publicly funded universities and hospitals are doing), but in the later stage (clinical trials) which needs deep pockets and appetite for risk, which only big pharma has, because they see a potential big payout.

I think the examples should make it more clear. Thanks to the high resolution of the data, you can see subtle changes in the slope (aka relief aka microtopography) that could hint to underlying remains of human settlements (usually some suspicious geometric patterns that you would not expect in a natural terrain).

See also here for an in-depth discussion on the potential use of such data: https://www.mdpi.com/2072-4292/15/6/1569

How do you suggest to change the description to make it less confusing?

Hijacking this thread: what's currently the cheapest way to get structured data out of a PDF?

I assume there's some reasonable tool out there to convert PDFs to Markup and than feed it to some LLM API with okay costs (Gemini? DeepSeek?). Any suggestions?

So in "Paskalampi" and "Vesijärvi", which part of it means "lake"? Naively (I have obviously no clue about finnish), I would have expected some syllables (or token in modern LLM terminology) to occur in both names (i.e. representing the "lake" part).

Has anyone worked on AI/ML approaches for detecting ancient structures in LiDAR data? Given that training data for identifying remnants of man-made structures (e.g., Roman or medieval ruins) is quite sparse, how would you approach this problem?

Some initial thoughts:

- Data Augmentation: Using synthetic or simulated LiDAR data from known structures to improve training. - Few-Shot Learning / Transfer Learning: Training models on better-documented archaeological sites and applying them to new areas.

Would love to hear thoughts from people with experience in remote sensing, computer vision, or archaeology!

So the AI is trained from the previous frame and the input and tries to predict the next frame, correct?

How could you achieve object permanence this way? Will it 'automatically' appear given more training data or more hidden layers? How is this handled in other approaches?