I work on the team that works on Calls. Thank you for the kind words.
It is true, both media and signaling is over anycast and advertised from every Cloudflare location. We manage things like ICE and DTLS state in a distributed way.
Super happy to be part of the super talented team that made this happen!
It's definitely appropriate to apply to multiple job posts at once. Jobs are reviewed by different hiring managers who look at your application independent of other jobs you may have applied.