dbcooper

There have been a few similar posts on HN recently for working with MS Office docs:

https://github.com/iOfficeAI/OfficeCLI

https://github.com/rcarmo/python-office-mcp-server

https://github.com/espressoplease/smalldocs

It would be great to see some benchmarks for token use, correctness, features etc.

A "standing review agent" seems to be one of the main differences beyond the new connectors and in place visualisation tools.

A standing reviewer agent. This runs in the background during a session, checking citations against sources, flagging numbers it can't trace back to evidence, and catching figures that don't match the code that supposedly generated them. That's not something Code or Cowork do automatically — you'd have to ask Claude to double-check itself as a separate step.

I had the same experience with a prompt about an antibody's structure and properties.

A few implementations listed on LM Studio. Any recommendations for which one to use?

Love this site for communicating the properties of WiFi protocols.

Yes, very questionable. They also missed New Zealand which is the largest exporter of dairy products (~ 21%).

Nature Food is one of those also ran journals that sully the brand. None of my colleagues in related fields bother with it.

The Netherlands is almost legendary for its agricultural productivity. Its greenhouse operations were the model for NZ capsicum production and other efforts. It also leads food science research in some areas. Wageningen is perhaps the best in that field.

"The 60 Minute Zoom" is a good short story to start with.

Will this convert websites into RSS feeds? Can I run a daily update on them?

Interesting video on the history of Worcestershire Sauce (fermented anchovy base):

https://www.youtube.com/watch?v=0q5QhGnEKUM

Addendum: https://www.youtube.com/watch?v=RvF2m57_Usg

Worcestershire Sauce (fermented anchovy base) with eggs is a classic combination for a reason.

A friend of mine has worked in TV and film for decades. Many times he has told me about rumoured offenders (typically after they are arrested), but other than avoiding working on productions with them what are his choices? Trying to do a completely ridiculous "citizen's arrest"?

For those interested in radioligand therapy against FAP antigen expressing cancer, Ratio Therapeutics is recruiting for a Phase 1/2 Open-label Study (NCT07156565).

Eligibility requires history of relapse and refractory soft tissue sarcoma. Recruiting in US and Canada.

https://clinicaltrials.gov/study/NCT07156565?tab=researcher#...

https://www.nytimes.com/2025/12/31/magazine/ukraine-ai-drone...

Would it be possible to ship a high performance, lean "modern" Windows, with legacy apps etc run seamlessly in VMs or containers?

https://x.com/EnterpriseCPU/status/1972103355012124891?s=20

From the Roddenberry archive:

https://roddenberry.x.io/2271-uss-enterprise-ncc-1701-major-...

A key limiting factor for dietary use of single cell protein is the high mass fraction of nucleic acid, which limits daily consumption due to uric acid production during metabolism. High rates of RNA synthesis are unfortunately necessary for high protein productivity.

The paper notes:

It is important to note that MP products often contain elevated levels of nucleic acids, constituting ~8% of the dry weight [17], which necessitates consideration when assessing their suitability for human consumption. To address this, a heat treatment process is employed at the end of fermentation that reduces the nucleic acid content in the fermented biomass to below 0.75/100 g, while simultaneously deactivating protease activity and F. venenatum biomass. However, this procedure has been observed to induce cell membrane leakage and a substantial loss of biomass, as evidenced in the Quorn production process [17], which also utilizes F. venenatum as the MP producer. Our experimental trials have encountered similar challenges, achieving a biomass yield of merely ~35%, and observed that heating process increased the relative protein and chitin content (Figure 2D,E), which may be related to the effect of membrane leakage, while the intracellular protein of the FCPD engineered strain was less likely to be lost to the extracellular. Thus, concentrating the fermentation broth to enhance protein and amino acids content in successive steps to produce a highly nutritious water-soluble fertilizer appears to be an effective strategy for adding value to the process (Figure 1).

The challenges of developing economic single cell protein products, that are suitable for human consumption, are described in chapter 3 here:

https://www.researchgate.net/profile/Martin-Hofrichter-2/pub...

wushowhide.diagcab

There's a tool for blocking selected driver updates that still works on Windows 11. Very handy.

Nick Mullen should be the guest of honor at this event.

What chemistry would they use for the photoresist type resins?

Can't even read the abstract without paying. That's a new low.

Yep. Enable extensions in edge://flags/. Then you can use ublock origin. You can install any crx file extension if you enable developer mode.

I'm running it on a device with a Qualcomm SM8635 Snapdragon 8s Gen 3 chipset, and it just crawls. The UI is very unresponsive, and page load times are terrible.

For youtube background play Brave is much better.

Firefox for Android is some of the worst software I've ever used. A lot of extensions won't work in it, and even Edge Canary is far better with them. It is extremely slow, and the UI is horrible.

I'm running it on a device with a Qualcomm SM8635 Snapdragon 8s Gen 3 chipset, and it just crawls. The UI is very unresponsive, and page load times are terrible. It also has to reload the page if it was running in the background and you switch back to it.

Does this work for videos flagged as age-restricted, or paid subscriber content? IIRC, yt-dlp needs to be passed browser cookies to do so?

You can use nextdns for DNS adblocking.

Overview publication:

https://www.nature.com/articles/s41591-025-03834-0

Anyone have a spare invite?