HN user

ck_one

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twitter: @janruettinger

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github.com 2y ago

Show HN: Go framework with builtin OpenAPI support

ck_one
8pts2
ai.googleblog.com 2y ago

Google AI Health: new AI model trained on free text radiology reports

ck_one
2pts0
news.ycombinator.com 2y ago

Ask HN: What service do you use to store your medical record?

ck_one
1pts0
news.ycombinator.com 3y ago

Ask HN: When is it NOT better to ignore competition as a startup?

ck_one
1pts0
news.ycombinator.com 3y ago

What do you use for health insurance as a founder only early startup in the US?

ck_one
1pts2
news.ycombinator.com 3y ago

Ask HN: Should a German founder with a green card set up a holding company?

ck_one
39pts37
news.ycombinator.com 4y ago

What happens to the hardware (MacBooks, Monitors, Chairs) of failed startups?

ck_one
38pts26
techcrunch.com 4y ago

Appstore for SaaS Tools

ck_one
3pts0
news.ycombinator.com 4y ago

Ask HN: MoonPay vs Stripe - who will become the web3 payment solution?

ck_one
12pts34
cointelegraph.com 4y ago

Bootstrapped crypto onramp and payment company valued at $3.4B

ck_one
1pts0
medium.com 4y ago

NFT startup Sorare raises new round: $600k (seed:2019) - $680m (Series A:2021)

ck_one
4pts0
news.ycombinator.com 5y ago

Ask HN: Do SWEs harm themselves salary wise by not returning to the office?

ck_one
3pts1
news.ycombinator.com 5y ago

Ask HN: How to study programming language theory as a non CS student?

ck_one
21pts25
clubhousebio.xyz 5y ago

Show HN: Edit your Clubhouse bio from your desktop

ck_one
3pts4
cvpr20.janruettinger.com 6y ago

Show HN: CVPR 2020 unofficial statistics, with better search functionality

ck_one
40pts13
www.immigration.net 6y ago

News of a Proposed Immigration Proclamation on Non-Immigrant Visa Holders

ck_one
1pts1
news.ycombinator.com 6y ago

Ask HN: Is YouTube Profitable?

ck_one
1pts0
news.ycombinator.com 7y ago

Ask HN: Resources about the fundamentals of programming languages?

ck_one
1pts0
news.ycombinator.com 8y ago

Ask HN: Have you done any courses by Devslopes ?

ck_one
1pts0
sharpsightlabs.com 8y ago

Math isn't an important prerequisite for ML

ck_one
1pts0
news.ycombinator.com 9y ago

Ask HN: Do you know any fun science/maths books for a casual read?

ck_one
1pts4
news.ycombinator.com 9y ago

Ask HN: Where can I find code of production level projects using sass?

ck_one
2pts0
ig.ft.com 9y ago

Election in France – decision about the future of Europe

ck_one
1pts0
www.economist.com 9y ago

Warren Buffett extends his dominance of retroactive reinsurance

ck_one
1pts0
news.ycombinator.com 9y ago

Ask HN: Looking for Communication Systems lab manuals using Simulink/Matlab

ck_one
1pts0
news.ycombinator.com 9y ago

Ask HN: Looking for clean frontend code to learn from

ck_one
2pts0
www.mailbutler.io 9y ago

Show HN: Smart Apple Mail Plugin

ck_one
1pts0
www.ft.com 9y ago

Sardinia – Island with its own currency

ck_one
3pts0

Most patients get tinnitus after hearing degradation. So my first advice is to do a hearing test. You mentioned you visited a doctor, was your hearing normal?

Tinnitus is still in the early stages of research. But the notion of just accept it, it can't be fixed will not be true forever. Researchers just recently started to cure some form of genetic hearing loss. That means one part of the puzzle of transporting gen editing viruses to the inner ear is solved. Next up is figuring out what gen edits are necessary. The field gets surprisingly little funding even though we have an aging population and lots of veterans with hearing issues. Many labs have tiny budgets <1 Mio per year but are making good progress every year. My guess is when one of the rich founders gets it (Elon, Sam, Larry, Brin etc) and decided to do something about it we will see real progress.

Claude Opus 4.6 6 months ago

It didn't use web search. But for sure it has some internal knowledge already. It's not a perfect needle in the hay stack problem but gemini flash was much worse when I tested it last time.

Claude Opus 4.6 6 months ago

When I tried it without web search so only internal knowledge it missed ~15 spells.

Claude Opus 4.6 6 months ago

If you just ask it you don't get the same result. Around 13 spells were missing when I just prompted Opus 4.6 without the books as context.

Claude Opus 4.6 6 months ago

Just tested the new Opus 4.6 (1M context) on a fun needle-in-a-haystack challenge: finding every spell in all Harry Potter books.

All 7 books come to ~1.75M tokens, so they don't quite fit yet. (At this rate of progress, mid-April should do it ) For now you can fit the first 4 books (~733K tokens).

Results: Opus 4.6 found 49 out of 50 officially documented spells across those 4 books. The only miss was "Slugulus Eructo" (a vomiting spell).

Freaking impressive!

In many fields there is no moat. It’s an execution battle and it comes down to question: can the startup innovate faster and get to the customers or can the incumbent defend its existing distribution well enough.

Microsoft owns GitHub and VSCode yet cursor was able to out execute them. Legora is moving very quickly in the legal space. Not clear yet who will win.

Pretty cool what they are working on. However, I wished there would be more funding for restoring hair cells which are the root cause for most people with hearing loss.

Researchers are getting closer. Dr. Chen from Harvard was able to regenerate hair cells in mature mice last year.

The problem is also becoming more widespread. 30 Mio people in the US and 400 Mio people worldwide have disabling hearing loss. Regenerating hair cells and the synapses around them would also cure Tinnitus. 30 Mio x $5k for a treatment = $60B market (probably way bigger with aging population)

I think we probably need more rich tech billionaires to get affected to attract large funding.

What billionaires that you know are affected besides:

- Brad Jacobs

- Ryan from Flexport/Founders Fund