barbarr

He doesn't need the money though. I bet there's something cultural or structural going on at GDM that made him want to leave.

Going off the other reply, I wonder if a highly-active secondary market means that companies can raise series [A-Z]+ rounds effectively forever, where each "round" just refers to a giant purchase of shares under strict company supervision. Is this the new game for startups?

So... Does the Gates foundation get an equity stake?

Unrelated, but I see the use of the phrase "taste" as having a strong Twitter / e/acc smell (in a negative way).

I tend to associate it with folks who are prepared to victim blame researchers for not adapting to the "new economy" as being people who have "bad taste" or "low agency", maybe as a way to rationalize/justify the upcoming inqeuality that AI will create.

Basically a recycling of the way "IQ"/smarts/hard-work has historically been used to justify disproportionate rewards for the upper class.

(Obviously a gigantic stretch on my part, and not saying the author is in this camp, but just wanted to vent somewhere)

I feel he'd want to rebut the use of an LLM for this task to begin with (i.e. find issues/nitpicks with the LLM judgment whether it said he's right or wrong)

Can't wait to see Gary Marcus's rebuttal

Getting SBF vibes from this. "Earn to give" is an inherently flawed philosophy.

It's Claude Code slop

I can't believe he was calling Greta a potential antichrist when there's... this

This is already the case

Why are we pushing this when we have beans

He smirked. "Yes, I am."

The comments there are hilarious

+1, the tokens from before a quantum hack will be transferred to a new fork. So at that moment, the value of BTC will go to 0 and the value of BTC v2 will take the value of BTC.

However at the moment, the community seems to be leaning towards pay-for-quantum-resistance [0]

[0] https://github.com/bitcoin/bips/pull/1670

This and stock buybacks make me question company valuations

Instagram reels are gonna get crazy

Why is apple doing protein folding?

Was a bit scared by the headline at first

To what extent is YC's current strategy a form of "cookie-licking"? I.e. capture a small fraction of every plausible startup created by the next generation of students?

I'm guessing they were looking for preferential delivery to certain cell types, and AAVs just happened to have best profile for those. If anything, LNPs might aggregate in the liver even more than AAVs, which can lead to even worse hepatotoxicity if an immune response happens.

The issue was not the gene therapy itself, but the delivery mechanism. They used a virus to administer the gene therapy, and this virus (like most bloodstream impurities) aggregates in the liver. At low doses this is fine, but at high doses, your body's immune response will be laser-focused on the liver, and you die from the side effects of this response.

Same, ever since AI got big I've started to see typos and signs of amateurism in a positive light. I wonder how long it will be before people start generating slop with typos on purpose so that we think a human wrote it. Maybe we're already there.

Very cool showing the outputs of hyperparameter search. Hopefully this gets someone out of a tuning tarpit!

ohhh, yea I terribly misread that

That puzzle has two solutions no?

     1 1 1   
     1 1 1 2 1
   2 x x . . .
   2 . . x x .
  11 x . . x .
  11 . x . . x
   1 . . x . .

     1 1 1   
     1 1 1 2 1
   2 x x . . .
   2 . . x x .
  11 . x . x .
  11 x . . . x
   1 . . x . .

Wait, what about it made you want to throw up? Was it that the proceeds from lawsuits were being garnished by the law firm rather than going towards the families?

I have a criticism that is the opposite of the article. We already know an immense amount about animal welfare and have done relatively little about it. Even if the AI welfare research is true, what are the chances we'll actually act on it?

The author claims that "machine learning methods better describe many biological systems than traditional mathematical formulations", but I see very little concrete evidence in the article to support it.

This might not be a bad idea. Setting up satellite institutions in other countries as backup, for example.

You're ignoring that the average ride on Muni, Bart, or AC Transit involves someone who's visibly or audibly tweaking out, loudly muttering curse words or threats to themselves / others, blasting music in the back from a tinny phone speaker, carrying a bag of cans and/or trash, or smelling offensively bad. It's no wonder that people won't want to take transit.

Source: someone who takes transit almost daily and has seen a LOT, and has received death threats on the bus twice in one year.