SemanticStrengh

I managed to make it crash by spamming letters: > Unchecked runtime.lastError: A listener indicated an asynchronous response by returning true, but the message channel closed before a response was received framework-a87821de553db91d.js:1 Error: code length overflow. (23804>23648)

cool project btw

This is the way.

It's not in space, see the theoretical limit being bypassed "List of the largest cosmic structure" https://en.wikipedia.org/wiki/List_of_largest_cosmic_structu...

As you can see, it clearly isn't homogenous https://en.wikipedia.org/wiki/List_of_largest_cosmic_structu...

The universe is not uniform/isotropic at large scales

That's one small step for man, but one giant leap for mankind.

Truer words have never been spoken.

we need to free ourselves from our chains

Scrum Elon Doge to the moon!

scrum is basically a way to provide fake jobs to many people, this allow them to avoid doing useful work and qualified work, like coding. The same applies to non-technical product owners. They are absolut frauds and will definitely not got to heaven, if there's one.

Scrum masters are a disease, rotten to the core.

I'd say thinking is the union type of under and overthinking. The approximation error he makes is a limit of our language. I propose to coin the word opti-thinking to fill the semantic gap.

I hate the fact that OpenSearch divide in a bipartite the human resources allocated at improving elasticsearch, which is a tragedy. The hypocrisy is strong at amazon, they have allocated a lot of engineers on OpenSearch and yet their number of contributions pre-fork drama was much much lower (although they were still an important contributor though). But once the management has control and developers can have their own NIH dopamine release, humans are eager to work.. For this human resources reasons, I hope the OpenSearch distraction dies in darkness. However, beside my utilitaristic goals, I am also one of the only person caring about the technology. And it happens that the technology is generally not found in ElasticSearch but in the much more salient project: Lucene, which it uses. However, despite its big humans resources, ElasticSearch does a great job at NOT exposing Lucene features and optimizations... Lucene especially has developped 2 major optimizations the last decade unexposed in ES, one being about shards (don't recall the name), the other being concurrent search. And it happens that the NIH syndrome at amazon allow them to at least reconsider those frozen choices in ES. https://github.com/opensearch-project/OpenSearch/pull/1500 And I am eager to see the performance implications it will have although the ES approach has some pros too. In this issue, I descibe what ElasticSearch would do for parallelism, in an ideal world: https://github.com/elastic/elasticsearch/issues/80693

I suspect that my opinion is just as much gibberish as yours clearly is, but with more self-awareness.

OK thank you layman for your ad-hominem, I have extensive expertise in medecine and pharmacology and have extensively studied the thymus, spleen, associated peptides and immune and aging biomarkers, so what seems to you as gibberish is actual valid statements or for a few ones, very reasonable and necessary to be asked speculations. But indeed, an expert is often difficult to distinguish from a bullshitter when the layman lacks discernment, a formation in epistemology nor care to check any of the sourced premises.

why would that "budget" be "for vaccines" _only_ ?

Well for starters I do not question wether there is a budget limit, there is it is a fact. I even explain in detail that a necessary component in the equation are naive lymphocite T and that aging and environement stressors induce an atrophy (involution/shrinkage) of the thymus and therefore of the total number of differentiated mature lymphocytes T. Also obviously I do not say that this only apply for vaccines, real covid is not much different from the spike protein and in fact induce more damage, however the question has to be asked, regardless.

consider what answer would have better evolutionary fitness

and yet having a limit is an evolutionary fitness as show the existence of thymus involution, both for reduced energy use and programmed aging evolutionnary benefits as shows the many papers on the topic. Obviously, as you should have guessed, the limit only matter to not be reached before the age of reproduction, which is < 20 years old

I am wondering how much immune "budget" do humans have for vaccines? This topic is left unadressed and is extremely worrying, being an existential risk. Basically, the body has a limited amount of unspecialized naive T cells in its lifetime, mostly located/modulated in the thymus gland, which involute quickly with age.

I suppose that 1) vaccines increase the rate of specialisation of naive T cells to mature t cells (hence the number of naive t cells diminish supraphysically)and I also believe that

2) those specific mature T cells, generating covid spike protein specific antibodies, have lost some or total ability to fight non-covid diseases as a cost of specialization. 1) would increase thymus involution rate and therefore age speed of immunosupression.

2) would reduce generic immune ability (learning other pathogens)

3) I believe the increased immune profile after a vaccine induce a long lasting (at least 6 month) increase of accelerated aging process in humans, via increased inflammation and therefore apoptosis, DNA mutations and oxidative stress, although in a mild form and hence in the medium term asymptomatic.

Above all the premises I enumerated, the 2) is the one I would draw the most attention to, which can be reformulated as: do the repetitive administrations of a vaccine (here the 3 mRNA doses), reduce the effectiveness of the immune system for future non-COVID diseases, and even more importantly, does those doses reduce the immune learnability budget and therefore do those vaccines reduce the effectiveness of future vaccines against the next non-COVID pandemic? There has to be a limit to immune memory, the question is, after how many vaccines do the effect become non-negligible on aging?

study backing chronic inflammation and therefore accelerated aging: > vaccine-induced hypermetabolic lymph nodes https://pubmed.ncbi.nlm.nih.gov/34857663/

study backing the depletion of lymphocite T helper cell production: Study Shows Immune Cells Against Covid-19 Stay High in Number Six Months After Vaccination https://www.hopkinsmedicine.org/news/newsroom/news-releases/....

Moreover, I have an issue understanding why would vaccine not massively lose effectiveness after the age of 70 since at 70 the thymus has ~completely involuted (although maybe the stem cells in the bone marrow suffice?).

Is there a way to prove that you own an old bank account with X money in it? Or better, to be able to exhaustively list your bank accounts and their respective amounts? Well a salary bill pay document should be enough though if not falsifiable.

I think there is an untapped market for people willingly paying some people to watch/monitor them achieve their desired goals consistently. It's similar to beeminder and bodydoubling or r/GetMotivatedBuddies except it would be much more effective because of professionalism. On beeminder there's not check if you being honest/accountable. On GetMotivatedBuddies you generally find unreliable people AND you must coach them too. On bodydoubling websites, people are watching each other but there's generally not interactions, just eyes. And no professionalism.

The one that will build this will enable a disruptive market where people can finally become much closer to their ideal self, by the effective means of social pressure, real-time e-coaching and monetary incentive. Does this actually exists?

Twitter characters limits is the negation of intelligence

Any NDA that works worldwide or at least for European countries??

the majority of the damages of a stroke are generally induced in the following weeks of the event, e.g. via extremely high oxidative stress and apoptotic signaling and impaired bioenergetics. Those issues are trivial to fix pharmacologically speaking and indeed there are countless studies showing a very potent protection against damage including neurons death, unfortunately doctors have not the required erudition nor do they care to save those lives and therefore people are left helpless and suffering.

How much energy loss has the system? And what complexity curve fit its efficiency over length?

If they invested instead a mere Billion into optimizing a fork of e.g. QEMU they would destroy VMware in performance.

Yes and it's called Kotlin

Pre woke tools, wouldn't have been allowed nowadays.

Smoking these meats! https://youtu.be/YeemJlrNx2Q

Is brocoliman standing in the way? :(

Yes metaculus mostly bet a magic number based on perhaps and tbh why not, the interaction of NLP and vision is mysterious and has potential. However those magic numbers should still be considered magic numbers. I agree that in 2040 the interactions will have extensively been studied though but the conclusion of wether we czn go much further on cross-models synergies is totally unknown or pessimist.

This competitor might be better for respecting spatial prepositions and photorealism but on a quick look i find the images more uncanny. DALL-E has IMHO better camera POV/distance and is able to make artistic/dreamy/beautiful images. I haven't yet seen this Google model be competitive for art and uncaniness. However progress is great and I might be wrong.

Note that there was a close model in 2021 ignored by all https://paperswithcode.com/sota/text-to-image-generation-on-... (on this benchmark) Also what is the score of dalle v2?

Does it outperform DALL-E V2?