Inflammation predicts 25% higher mortality

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00230-0/fulltext

by brandonb • 11 months ago

24 4 11 months ago

brandonb2• 11 months ago

This study followed 5,294 people for 20 years. People in the highest third of inflammation (hs-CRP > 5) had 32% higher chance of heart disease and 25% higher mortality from any cause.

Inflammation was a predictor even when you take cholesterol, blood pressure, BMI, etc into account. (The researchers trained various models to test this.)

Inflammation is pretty easy to measure in a blood test. Lots of places online: https://www.empirical.health/product/comprehensive-health-pa...

hinkley• 11 months ago

Luckily I can only be 100% dead.

duffpkg• 11 months ago

This headline is heavily editorialized and does not correspond with the title or findings of the study linked.

brandonb2• 11 months ago

The paper's original title is 66 characters too long for HN.

The "25% higher mortality" comes from the all-cause mortality result in "Findings", which is one of the main results of the paper. The paper expresses it as a hazard ratio (HR) of 1.25 [1.10–1.42]. Hazard ratios are standard in medical research, but I wanted to summarize the main result without jargon.

Inflammation predicts 25% higher mortality

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