High levels of antihistamine drugs can reduce fitness gains

https://medicalxpress.com/news/2025-06-high-antihistamine-drugs-gains.html

by bikenaga • 1 year ago

14 4 1 year ago

medicalxpress.com

UK-AL• 1 year ago

Ma gains

I have awful hay fever, so take them religiously.

username44• 1 year ago

This is really interesting, as I came to a similar conclusion recently. I was taking famotidine (h2 blocker) and fexofenadine (h1 blocker) and noticed my daily running routine became significantly more difficult. Within a few days of stopping both, it became easier again.

jameskilton• 1 year ago

Important note, but still very interesting research!

Halliwill emphasized that the new studies and other related research use very high doses of antihistamines, much higher than what a person would consume to combat allergies. More evidence is needed to know whether a low-dose daily allergy medication could interfere with fitness.

AnthonBerg• 1 year ago

Having had to figure out a physiological puzzle involving histamine as an alertness-promoting neurotransmitter, and getting to see adult-onset Type 1 diabetes up close where histamine is intimately related to everything as a core part of glucose metabolism – both these aspects of histamine are well known but surprisingly underdiscussed! — I have come to see histamine as sort of a “tissue opener” signal. And with all as the vantage point, the perspective afforded even just by the headline makes immediate and intuitive sense.

High levels of antihistamine drugs can reduce fitness gains

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