Booster jabs 'massively' strengthen the body’s defenses against Covid

https://politicalwire.com/2021/12/03/booster-results-raise-hopes-of-beating-omicron/

by MilnerRoute • 5 years ago

9 15 5 years ago

_red• 5 years ago

Imagine needing to get boosters every 3 months and being so insane you think its working....

rsynnott3• 5 years ago

I mean, hopefully we don't end up in that situation, but it would still clearly be better than _not_ having the boosters, if what's where we do end up.

nojokes• 5 years ago

Is this comment about UK decision to give boosters after 3 months from last vaccination?

I think there is big misconception about boosters and Delta. People appear to assume that there is some time after what vaccines loose effectiveness against Delta.

I see it rather as assumption that 1 shot should work against Wuhan variant. Well, it does not so does not 2 shots against Delta. Waiting period is irrelevant. It is only a compromise between mounting a better immune response from time difference and risk of infection.

guilhas• 5 years ago

The vaccine initially 90%+ protection was so good we were all going to be "free", amazing...

_Microft• 5 years ago

The vaccines as they are would have been perfectly fine if the wild type of SARS-Cov2 were everything we had to deal with. At least you seem to be referring to that because of the level of efficacy you mention. Unfortunately the pesky Delta variant appeared and threw a spanner in our works. Now there is the Omicron variant which seems to be even more infectious.

As much as I understand that people would prefer if the world were simple and solutions obvious but it just not is this way. It's messy and things change and that means that yesteryear's statements just might no longer be true. We need to deal with that and please do not make things more complicated than they are anyways already.

sigmaprimus• 5 years ago

plus if there was actually something bad in the first two doses, how else are they going to undo the damage without a third shot? After all yesteryear's treatment might no longer be a treatment at all and we might need to deal with that as things turn out to be more complicated than "Two weeks to flatten the curve".

pacerwpg• 5 years ago

It initially was 90%+ protection.

rsynnott3• 5 years ago

Versus the variants available at the time, yes. Unfortunately, the people running the studies couldn't get the budget for a time machine to see what would be happening in late 2021.

Note that the possibility of future variants was certainly raised at the time; it was never any secret that this was an evolving situation.

anramon• 5 years ago

So, saying that vaccination should be primarily and aggressively focused on people with comorbilities can be "misinformation" but saying that booster jabs "massively" strengthen bodys's defense against covid is completely accuarate and acceptable.

I think we are really getting into a point of no return here, i'm actually seriously worried about all this.

rsynnott3• 5 years ago

So, saying that vaccination should be primarily and aggressively focused on people with comorbilities can be "misinformation"

Eh? That's not misinformation and has been the policy of most governments, more or less. Now, it would be misinformation to suggest that it doesn't need to be given to anyone else.

but saying that booster jabs "massively" strengthen bodys's defense against covid is completely accuarate and acceptable.

That is what the studies say (obviously, 'massively' is editorialisation).

I'm not sure what your point is, here?

impendingchange• 5 years ago

Perhaps that editorializing seems to push a narrative, when the Lancet study doesn't contain the word "massively" at all.

To quote the single-sentence summary of the study, "All study vaccines boosted antibody and neutralising responses after ChAd/ChAd initial course and all except one after BNT/BNT, with no safety concerns", flies in the face of what most people anecdotally know with regards to vaccine safety, which could be interpreted as "pushing a narrative".

https://openvaers.com/

disabled2• 5 years ago

Yep. Getting boosted (getting a booster) confers secondary immune response. The initial jabs only confer primary immune response.

See this for more info: https://bio.libretexts.org/Bookshelves/Microbiology/Book%3A_...

giardini• 5 years ago

I find the use of "primary" and "secondary immune response" to be misleading. FWIW

"As Hopkins Medicines suggests, the third dose of the mRNA COVID-19 vaccines- Pfizer and Moderna- is *identical* to its first two doses. "[emphasis mine]

From

https://www.republicworld.com/technology-news/science/is-pfi...

tinus_hn• 5 years ago

So what kind of response are we going to get from the next booster shots that have already been announced? The tertiary immune response?

disabled2• 5 years ago

We don't know if an omicron specific booster will actually work due to something called "Original Antigenic Sin". For more information, consult this: https://www.sciencedirect.com/science/article/abs/pii/S08968...

If you are eligible for a booster, then you should get one ASAP. The original coronavirus vaccine antibodies present in your body will cross-react, to a certain degree, with omicron.

Booster jabs 'massively' strengthen the body’s defenses against Covid

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