HN user
This is probably one of those areas where one symptom cluster (CFS) can be caused by several different things (COVID, autoimmunity, EBV, etc). So original causes may be different but they all converge on the same major symptoms.
Antibodies were detected, not their activity. Here's the assay used: https://www.cell.com/cell-reports-methods/pdf/S2667-2375(22)... Measuring antibody activity is a lot harder than measuring antibodies, just being able to assess antibody targets in a high-throughput manner is a huge and very recent step forward.
This is great news for a few reasons:
1) Clear molecular signals of pathology mean that minimizers' claims that longcovid is just psychosomatic or malingering are unsupported.
2) Seeing high antibody titers against COVID & EBV adds weight to the viral persistence and reactivation hypothesis: longcovid may be due, in part, to ongoing low-level infection elsewhere in the body along with reactivation of other viruses like EBV or HPV.
3) Autoantibodies were found again, but not significantly different than those seen in non-longcovid control groups, which is interesting because it had been suggested that longcovid may induce immune quality control dysfunction and increase overall autoimmune reactivity.
Hopefully these results can help guide better study design and management for longcovid trials.
I personally know the man who conceived of this app, and I can attest that he does very solid work. From poking around Babo thus far, it seems that he has yet again made a solid app.
Now I just have to figure out what to sell.
Agreed. Monetizing dress.me as a preferred associate of clothing sites, or as a walled garden market where only you can offer select deals, would be far more palatable. I am also in your target demographic, but all I want is an algorithm that tells me when polka dots and stripes don't match.