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webdevatlurk

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This seems really nice as a sketchpad for small flowcharts. I'd definitely use it to map out a small piece of work, because I'm terrible at laying out flowcharts on scrap paper without wasting space or painting myself into a corner.

One minor annoyance: I can't use tab/shift+tab to indent or dedent lines.

From the Wiki page for Furin

...must be cleaved by furin or furin-like proteases to become fully functional. Anthrax toxin, pseudomonas exotoxin, and papillomaviruses must be processed by furin during their initial entry into host cells.

From the sound of this:

- the site on the virus gets cleaved - Furin enables the cleaving - Furin exists in hosts cells

What I think I understand is, the cleaving makes it easier for the virus to reproduce inside the cell?

edit: turns out I have no idea how to format things on HN

I have no idea if molten salt reactors are as awesome as this website represents them to be, but I thought the following point was interesting:

"light water reactors can use only about 4% of their available energy."

They're comparing with 1960s reactors designs, so maybe more modern water reactors are more efficient. But, it's still amazing to me that there's that much more energy that we could potentially harness from the fuel.

It's well documented in numerous reports that:

1. The position and size of the upgraded engines for the 737 MAX caused the plane to tend to pitch upwards, which could cause a stall. 2. Boeing was concerned designed MCAS to automatically push the plane's nose down to prevent stalls

Every single piece of reporting I've seen on the matter refers to MCAS as an anti-stall device.

Pilots of 737 who have talked to reporters refer to it as an anti-stall device.

I have a hard time believing that this information hasn't been fact checked to hell and back yet.

Why would you want the IRS to duplicate this effort and compete with these companies?

Is tax collection not a function of the government? I'd rather my taxes fund a free, easy tax filing system than pay fees to rent seeking middle men. Those fees are just an inflated tax by another name. We should be eliminating those kinds of taxes, not entrenching them.

If they do it in-house, do they even have the expertise?

Government websites and software have a reputation for being ugly, slow, broken and poorly designed. Government is also capable of building good tools. Two organizations that have done good work and could conceivably work with the IRS are:

- https://www.usds.gov/

- https://18f.gsa.gov/

I'm also pretty sure the IRS has plenty of expertise around the filing of federal tax returns.

Everyone needs to file state taxes anyway.

I don't see your point? Everyone will continue to file their state taxes separately, electing to use or not use available tools, as they always have.

They might be a good answer for newbies that want to spend 100$ on a stock for the first time, but for anything else I will stay with Ameritrade. Thanks

I don't think you're their target audience. Their marketing materials say things like "democratize markets", "investing for the rest of us" and "learn to invest in the stock market". Also notice that the screenshots of their app feature portfolios with low dollar amounts, compared to the larger dollar amounts the big-boy brokers use as examples in their marketing.

Because they're targeting newbies, and because of their behavior in that context, I think Robinhood wants to be your bookie more than they want to be your broker. The marketing pitch on their landing page reads "Robinhood lets you learn to invest in the stock market for free.", but the updates they've introduced while I've been paying attention to their app seem to be aimed at encouraging people to do risky, stupid things with their money. I assume they plan to monetize this somehow.

What follows are some examples of things I think are pretty scummy, given that Robinhood's target user is an investment newbie:

- They pressure new accounts into paying a monthly fee for what are essentially margin trading accounts, but the vast majority of people should not be trading on margin.

- They promote aggregated news stories from crap outlets like seekingalpha to their users, but curiously not educational material with sound investment advice. Another indication that their pitch about learning, which probably makes newbies feel safer using RH as a platform, is insencere.

- They added the ability to trade cryptocurrencies a short time back. The vast majority of people should not be investing in cryptocurrency. I tend to agree with Nicholas Weaver that most coin funds/offerings are basically scams or thefts waiting to happen. The values of the coins are volatile, and what happens if governments decide to make it difficult to exchange them for desirable currency? At least you can buy drugs on TOR, I guess?

- They recently added option trading. The vast majority of people should not be trading options. It's probably closer to straight up gambling than buying stock at random.

If they really wanted to open up markets to any average Joe with a smartphone and help them learn to invest, rather than encourage them to lose all their money, they wouldn't be prioritizing the things they have.

Just for contrast, you know what simple things Robinhood users can't do? They can't check the managment fees when looking at a fund. They also can't sort their portfolio into short and long term holdings before choosing to sell stock.

Finally made an account to post in this thread.

I'm rather early in my career doing mostly Ruby, Python and JavaScript things. As you might expect, I consume mainly Ruby, Python and JavaScript related talks.

The first two talks that really blew my mind are:

- K Lars Lohn's PyCon Keynote from 2016: https://www.youtube.com/watch?v=bSfe5M_zG2s

- Jim Weirich's (RIP) "Y Not" talk from RubyConf 2012: https://www.youtube.com/watch?v=FITJMJjASUs

There are many other presenters who I have a good opinion of:

- Raymond Hettinger: his presentation/teaching style is something I'd like to model my own after, also he gave the first talk on writing proper threaded/concurrent python that I was able to understand and make use of.

- Brandon Rhoades: another speaker with a presentation style that I've found easy to follow, also he takes a little shot at the dd utility about 18 minutes into https://www.youtube.com/watch?v=z9Hmys8ojno)

- Sandi Metz: I started out in Python land and moved to Ruby land, where I was introduced to Sandi's talks. She doesn't talk about incredibly complex topics, but she's got insight into some really basic things that's helpful to new people who can't see the forest through the trees.

- Robert Martin: I gather that his OO principles are not universally revered, but I find his talks useful.

- Gary Bernhardt: his talks are interesting and entertaining in ways that most are not

The list goes on, but I can't think of them all right now.