throwaway990909

Me, the first week was pretty hard, the next 6 months were still hard, the next year was a lot easier -- but I still want a cigarette with some frequency! It's just a "want" I can, now, after two years, fairly easily choose not to fulfill.

But when I see other people smoking in a context I remember being enjoyable, OR when I am especially stressed or depressed -- I definitely still want a cigarette. I don't especially think I'll ever never want a cigarette again.

They are so addictive!

Heroic is usually considered at least 5g

5g of actual mushroom fungus bodies? Yeah, this was just chemical psilocybin on it's own nothing else, and if I remember right the dose was consequently measured I think in mg rather than g, but they did use the phrase "sometimes called 'heroic'" when I asked about the dose, so, yeah, something like that. (They were clear that it was going to be a very large dose -- informed consent!)

So instead you'd train yourself to acknowledge all aspects of you in that moment and instead

The counselors/guides involved definitely had a sort of Buddhist philosophy, with regard to quitting smoking as well as the psilocybin session.

I find Americanized (not to be pejorative, just we're always in our culture) Buddhist philosophical approaches to be increasingly popular among therapist and mental health experts generally. But they definitely were here. I have an interest in them myself.

I do not actually think I have a particularly "open-fluid" mind, compared to others, but I guess I'm trying (-without-trying). :)

I wonder if the researchers first created a survey to determine the level of this kind of psychological flexibility a person has, and then see how those different groups perform in the psilocybin research

They definitely gave me all sorts of survey instruments, at various points in the study. Most of them multiple times, at various points before and after the session. It sometimes seemed obvious what they were "for" from the questions, other times mysterious. My sense is that while some of it may be, like you say, to see what kinds of people might have different outcomes -- more than this, I think a lot of it was to see if the psylocybin session changed people in what ways.

I don't think it actually changed me in a way that would show up on the survey instruments (I was kind of hoping it would!), but I haven't seen the analysis of my survey instruments, and I didn't keep copies of my answers!

I didn't exactly have any nausea.

But, I mean, my body did not feel... normal, including digestively. It did not always feel "right". I definitely went through some weird body things, and weird relationship to my body experiences.

It was a very large dose.

I have eaten mushrooms on my own before (although not for years), much smaller dose, and had nausea, so I know what you mean. This was a different sort of experience, that did not involve a 'normal' kind of nausea, my guess is that's because it was pure synthetic psilocybin, yeah.

They told me the weight, but I forget. It was a large "heroic" dose. The research protocol is perhaps already available somewhere (published paper, pre-print, registered study, not sure) which would have the dose.

They used manufactured/sythesized psilocybin compound in a capsule, not mushrooms or extracted from mushrooms.

I think they tried to take all the 'best practices' for quitting smoking and gave it to all participants, same experience up until quit day. On quit day, "control" group got a prescription for nicotine patch; "psilocybin group" got a session (and no patch!) -- the psilocybin group in this particular study was just one "heroic" dose session on smoking quit day, that's it.

Some of the supportive practices or suggestions included:

* just regular sessions, that were in some ways more or less like a "therapy" session focused on looking at smoking in your life. (whatever that means to you, it really was also just a good therapy session!)

* set your quit day near the beginning, several months before the quit day. Build up to it.

* at one period, every time you want to smoke, note what you feel like and what is precipating it, make a note of it. Develop a sense of what things make you want to smoke and why, and what role is has in your life.

* A "practice quit" day a month or two (I forget) before actual quit day -- just try not to smoke for 24 hours, see what it's like, knowing you can smoke again after that. Now you know what it's like, and that you got through the worst day, and what parts are going to be hardest and can develop more strategies for them.

* Get a clear list of the reasons you want to quit. Think about em. Write it down, to refer to it when it gets hard.

* Make a list of things you can do instead of smoking, after you quit. It doesn't matter if they are unhealthy (junk food or whatever), they're still healthier than smoking.

* after quit day, phone number of a therapist you've been working with, invitation to call or text if you feel tempted and need support and to talk through it. Therapist texted me daily checking in, seeing how it's going. (seriously, why DON'T we use techniques we associate with alcohol and other drug addiction treatment on cigarettes, you know? they are crazy addictive!)

There were other things too, additional like little cognitive-behavioral (I guess?) games/techniques. I don't even remember them all. I should have taken more notes on all of it! Just having people there rooting for you and to whom you feel kind of accountable to is big.

If their study really does show significantly more success in psylocybin group than control group, I find it meaningful that even the control group got really good support from good counselors. (And I still wouldn't say it was easy to quit!)

I was a participant (ie, research subject) in one of the previous rounds of studying psilocybin for smoking cessation at Johns Hopkins.

I was randomly assigned to the non-psilocybin "control" group. I still successfully quit smoking -- the "cognitive behavioral therapy" and just general support was great. The researchers showed genuine care, it wasn't like being a lab rat.

Because the study was designed with a "crossover" component, I still got the option, which I took, to return 6 months later for a psilocybin session. The session was interesting, but I wouldn't say life-changing. Probably. I am still a non-smoker, over 2 years after quit date, did the 6-months-post-quit session help? Maybe?

Ask me anything! Although I'm not sure what else there is to say!