Throwaway acct time!
I'm burnt out but there is no way on earth I would discuss personal problems with my boss, particularly ones that might indicate a potential work performance issue. I'd be handing this person a reason to actively start searching for my replacement. No way. I'm closing in on 40, which severely limits my options in Silicon Valley. I make a fairly decent salary, for a very well known tech company. Not gonna risk that. I've got kids and a mortgage to pay.
Quite frankly, I am shocked at the number of responses encouraging people to do this. It seems very high-risk, low potential reward. Interview when you can escape for a few hours, and if you happen to find a better job that looks like it will be less stress, take it! THEN and only then should you tell anyone.