True, but unfortunately those extra modifiers are now used up for getting the original keyboard back. If you want to do, e.g. Control-Shift-Arrow to select text, you now have to use even more modifiers. I'm currently using a Razer Anansi which is a full size keyboard with extra modifier keys under the space bar. Combined with AutoHotKey and Caps Lock, I can select text with the keyboard without moving away from home row. E.g. CapsLock + Ctrl(thumb) + Shift(thumb) + L does Control-Shift-RightArrow.
I do wish full size keyboards stopped wasting so much space with the space bar though, the way small keyboards do. That would put more modifier keys in the reach of your thumbs.