Blocking Google and Facebook using Ad Block Plus and Ghostery 12 years ago
don't forget about flash cookies, a.k.a LSO's or SuperCookies. BetterPrivacy works well mitigating that.
i'd also recommend 'Secret Agent' - "Continuously Randomizes your Firefox/SeaMonkey HTTP User Agent, to Suppress Device Fingerprinting, and Resist Web Tracking. Also Prevents eTag Tracking.": https://www.dephormation.org.uk/index.php?page=81
hosts file is another option: http://winhelp2002.mvps.org/hosts.txt