HN user
Have you seen this talk: http://www.ted.com/index.php/talks/eva_vertes_looks_to_the_f...
You may wish to add it to the wiki as a "non-traditional but scientifically verified" way of thinking of cancer. Very interesting. I wonder how far she got with the research since 2005.
I build absolutely everything on the top of PHP and the WACT framework. The latter ensures that my code stays maintainable and well-organized. It also emphasizes the use of design patterns. I'd never switch to anything else when it comes to web development and I'd have left the industry if there was no WACT. That's why I became one of its core contributors.
Not to take a stand, just FYI: PHP5 has built-in iterator support now and PHP 5.3 includes namespace support as well (TBR this month).