It's often said that to be outstanding, you should master two different fields then work at the intersection of those fields. For a lot of people the model of "real greatness" is Leonardo, who mastered about 7 fields.
To even get close to that you need to be the sort of person who changes fields every 5 years or so. I think this temperament is relatively fixed, perhaps because it's a feature of some kinds of neurodivergence. If ND and innate ability are both fixed, what you need to reach greatness is a bag of tricks like the author has so you optimise the many parts of personality and behaviour that are not fixed.
What I think is sad about modern times is, it's increasingly difficult and impractical to make a career change into a regulated profession. You can switch to CS, painting, or poker any old time. But if you're not a doctor by the time you're 40, forget about it. I bump into many people who are interested in medicine and would be great at it, but the switching cost is insurmountable. A shame because there's so much greatness to unlock at the intersection of CS, medical research, and clinical practice.