HN user

erhk

534 karma
Posts0
Comments242
View on HN
No posts found.

Any public communication is handled by people not machines. No one wants to make an automated status page because theres a shit ton of real noise that users dont need to hear about, nd theres a lot of outages that automation won't accurately catch

Mutations which improve transmission and longetivity will, in general, become more prevalent. Proliferation begets proliferation. You cannot transmit a strain if you are at home in bed from its severity.

Help me understand how a virus can replicate without being detected but can also increase its lethality.

We already have an asymptomatic and infectious incubation period. If that kept stretching longer then you are delaying the lytic cycle even longer? Or does propogation and ultimately viral load also happen as a slower burn? Eventually you will have damaged too many cells.

What does region mean in this context? A region of the body?

Antigen binding?

Your statement on future infections by a distinct antigen than you were immunized for is objectively true. A vaccine is not a panacea for all viruses.

If I prepare my home for a flood then I shouldn't expect an earthquake to be stopped.

If we are making the case that a surface protein is too targetted then I would point towards the seasonality of the flu.

Alpha was more lethal than delta from the sequencing reports posted by my State in the U.S.

.4% lethal compared to .3% lethal when I last checked.

So thats one goalpost. Another litmus test is that if delta was more lethal it would have been a very popular media talking point. Fear is unfortunately a successful motivator for clicks.

In fact the better the virus gets at infecting our cells and evading immunity, the more likely it is to also spread to dangerous / lethal levels before our immune systems are able to stop it.

Can I ask for some related literature on this topic? This contradicts my understanding.

Natural immunity isnt viable for the people likely to perish if they are infected.

Yes you should get vaccinated even if you tested positive because false positive tests can occur.

There is no verifiable record of anyone having been sick with covid in the same way that there is for vaccination.

"Immune system robustness" is not something quantifiable or comparable in human populations to my knowledge. We can identify immune system weaknesses or compromise but I do not know of a metric to rank individuals relative to each other.

If you trigger a memory response why would it matter if it was recalling a different similar protein? Wouldnt your immune system also remember and respond to a real pathogen, suggesting that the orginal vaccine was sufficient? In what world do you identify a pathogen but the fail to respond to it? Its not as if your body responds significantly differently to distinct illnesses.

Perhaps my understanding here is too cursory but this claim is pretty extraordinary for what I know.