chromatin

Looks like it will be a paid offering? Seems strange coming from a Fintech, unless they're looking to pivot.

A 1 gbe local network should have < 1 msec latency per hop so theoretical upper bound is substantially higher than 30 tps (again assuming instantaneous compute) => thus network latency should not be the limiting factor in reality, no?

I would very much like to see a Lightning-Network based 402 standard succeed!

The UX is awful - I bailed out at 25/100 JUST IN LEVEL ONE (BASICS)

Might I suggest adaptive difficulty? After getting 10, 15, 20 correct in a row it should scale up the difficulty immediately, rather than waiting for 100 in the basic level 1...

We noticed this years ago when looking at -- IIRC -- ikaros antibodies. They were clearly faked. Lacking any sort of platform to gain attention we moved on to Abcam and our lab just sort of maintained a mental map of who not to purchase ANYTHING immuno- from.

Do you need to predict when AP-MS is so cheap?

Yes because a core reason fro this technology is evaluation of de-novo designs (small peptide binders; scFvs; sdAbs)

If you had read the article, you'd have seen that UUIDv4 with Rowid was slightly slower than UUIDv7

Is this substantially different, cognitively or skills-wise, than moving into management and directing a team to write code, but no longer writing code oneself?

"Practice is policy"

I disagree and think GP poster is right on the money.

There are many ways in which inflation numbers are cooked; just one of them is the hedonic adjustment [1].

Others include an un-representative basket of goods.

The basket of goods is adjusted every 2 years, but not necessarily in a way that mirrors the way real households adapt their spending patterns to increased prices.

Owner equivalent rent (LOL) massively lags behind home prices.

Honestly, when 10s or hundreds of millions of people's perception does not match *Official Government Numbers*, then it's reason to suspect that the official numbers are a poor metric.

[1] https://www.bls.gov/cpi/quality-adjustment/

I love that you are doing this test. However, as it purports to be a test of "English-to-SQL", your hardest question (Q9) seems ungrammatical:

Show order lines, revenue, units sold, revenue per unit (total revenue ÷ total units sold), average list price per product in the subcategory, gross profit, and margin percentage for each product subcategory.

In particular, the clause "in the subcategory, gross profit, and margin percentage for each product subcategory" is ambiguous, and I wonder if more models would pass if the English were reformulated to be correct.

(it's also notable that Claude Opus 4.6 and Sonnet 4.6 both "missed" this one)

Incredible; I'll let my patients* on Home HD know about this.

*not a nephrologist but have several pts on home hd

Delve was founded in 2023 by Karun Kaushik and Selin Kocalar, both Forbes 30 Under 30 members and MIT dropouts who met as freshmen.

Forbes 30 under 30 remains undefeated

No, not at all. My unqualified internet diagnosis is that you may have high anxiety.

When I was a young(er) postdoc and had to overhaul my bicycle -- my main transportation to work-- this site was invaluable. Forever grateful to Sheldon.

According to linguists, elongated variations such as "heyyy" could be construed as flirtatious, "hellaw" might suggest you're from the southern US,

I am from the Southern US and I am definitely not familiar with this phonetic form. Could be what a BBC writer _imagines_ a Southerner sounds like

I found Croatian significantly easier than Czech, perhaps because of centuries (millenia?) of trans-Adriatic Italian influence?

Time is your most precious commodity.

Conduit [1] has retention policies [2] for media and attachments!

[1] https://conduit.rs/ and https://gitlab.com/famedly/conduit [2] https://gitlab.com/famedly/conduit/-/blob/next/docs/configur...

Intentionally not bothering to go into why, but above average intelligence.

Speaking as a geneticist, it's a shame that this is forbidden knowledge

I've found the same. I've moved from a homebrew tinkerer's delight home network with pfSense running in a VM, Supermicro FreeBSD ZFS fileserver, hodgepodge of cameras etc. to a top-to-bottom Unifi Stack.

My time is worth a lot more now, my family appreciates very much that it "Just Works" (tm), and -- most importantly -- the cognitive load for me is a fraction of before.

I am a natural skeptic, but in this case I think it is just an accident of history how different systems developed.

FWIW, although this is not well known, many medical schools offer combined BA/MD degrees, ranging from 4-8 years:

https://students-residents.aamc.org/medical-school-admission...

When I went 20 years ago, my school did not require a bachelor's degree and would admit exceptional students after 2 years of undergraduate coursework. However I think this has now gone away everywhere due to AAMC criteria

Partially true, and the answer to that is runway -- it will be a very long time before all the other specialties are fully augmented. With respect to "non-surgical" you may be underestimating the number and variety of procedures performed by non-surgeons (e.g. Internal Medicine physicians) -- thyroid biopsy, bronchoscopy, endoscopic retrograde cholangiopancreatography, liquid nitrogen ablation of skin lesion, bone marrow aspiration, etc.

The other answer is that AI will not hold your hand in the ICU, or share with you how their mother felt when on the same chemo regimen that you are prescribing.

The belief is -- and it is one that I share -- that this makes for more well rounded, human physicians.

Additionally, a greater depth of thinking leads to better diagnosticians, and physician-scientists as well (IMO).

Now, all of this is predicated on the traditional model of the University education, not the glorified jobs training program that it has slowly become.

My ZIP code happens to be shared by two separate cities and there are a few websites (Github, I'm looking at you) that will fail the payment, registration, etc. attempt if you don't enter the municipality that it THINKS is correct.

I think his point is that slavery is not outlawed by the 13th amendment as most people assume (even the Google AI summary reads: "The 13th Amendment to the United States Constitution, ratified in 1865, officially abolished slavery and involuntary servitude in the United States.").

However, if you actually read it, the 13th amendment makes an explicit allowance for slavery (i.e. expressly allows it):

"Neither slavery nor involuntary servitude, *except as a punishment for crime whereof the party shall have been duly convicted*" (emphasis mine obviously since Markdown didn't exist in 1865)

402 Payment Required

https://developer.mozilla.org/en-US/docs/Web/HTTP/Reference/...

Sadly development along these lines has not progressed. Yes, Google Cloud and other services may return it and require some manual human intervention, but I'd love to see _automatic payment negotiation_.

I'm hopeful that instant-settlement options like Bitcoin Lightning payments could progress us past this.

https://docs.lightning.engineering/the-lightning-network/l40...

https://hackernoon.com/the-resurgence-of-http-402-in-the-age...

The author makes the following assertion:

    Let me illustrate a common code organization issue some programmers run into on their first day. The novice writes

    terminal.print("Hello world")

    Then they decide they want to make the text red, so they edit their program to

    
    terminal.print("Hello world")

    terminal.setPrintColor("red")
        
    And then they're confused that it didn't come out red. They haven't internalized that the first line of code happens before the second. They just get a soup of code on the screen that kind of has the ingredients for a program, and expect the computer to do what they want.

I actually want lightning for my USB-C phone :/

Could be interesting, but I didn't see any /PICTURES OR VIDEOS/ of what I could create with this product.