Ask HN: Alternative CRM to Streak for Non-Gmail

I am a big fan of Streak, and if I were to use Gmail, I think I'd definitely use it. Yet, I really dislike using Gmail, and instead am paying for my own IMAP/SMTP host.

I am looking for a simple CRM solution that would be as effective as Streak (ideally, also in terms of its price point..).

Any suggestions?