Ask HN: Designing CVs for software jobs

I've been working in biology for a few years and have completed some Python/R projects along the way [see refs 1-2].

How do I describe/highlight these projects when applying for software jobs? I have experience writing CVs for biomedical jobs but not for software. How do I avoid having my application sent to the waste bin? Links to samples or general advice would be super helpful!

[1] http://ejstronge.net/

[2] https://github.com/ejstronge