Ask HN: My first project/maybe eventually startup

Hello HN. I'm building my first serious project, and I've got a general question for y'all. Is it a good or bad idea to integrate a few different APIs in the basic functionality of my site? I am considering using Dropbox for users' files, and MediaCrush for serving big media files. I apologize for vagueness...this project is nowhere near a point of being ready to talk about.

-sinwave