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Myelin repair promoted by clemastine fumarate in nonhuman primate model

https://www.pnas.org/doi/10.1073/pnas.2520161123

by bikenaga • 5 months ago

8 2 5 months ago

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Yapping7880• 5 months ago

Pretty interesting. There was a study about Clemastine use as a potential treatment/prolonging for ALS, but it did not show any significant benefit at preventing/delaying neuron death. I bring it up ALS because there are certain treatments for MS (like IVIG Infusions) that can also be beneficial for ALS patients.

https://pmc.ncbi.nlm.nih.gov/articles/PMC10568021/

pogue• 5 months ago

That's super unusual, as clemastine is another first generation antihistamine that's also anticholinergic. Other anticholinergic antihistamines have been shown to lead to increased dementia effects in users.

https://en.wikipedia.org/wiki/H1_antagonist

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