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We are all mosaics: genetic diversity found between cells in a single person

https://www.nature.com/articles/d41586-025-03768-0

by bookofjoe • 8 months ago

24 4 8 months ago

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4

bookofjoe• 8 months ago

https://archive.ph/9EEN1

Jeff_Brown• 8 months ago

The study is based on 100 cells from one 74-year-old man. The follow-up study will involve 150 individuals. I hope there's a very wide age range among them. They describe much, maybe all, of the variation as error, but one could imagine some of the variation actually serving a useful purpose and therefore existing even in young people.

d0ks• 8 months ago

Isn't the effect largely an age + lifestyle effect? Mutations increase as one ages, and things like smoking increase mutations (as the Nature write-up mentions).

_aavaa_• 8 months ago

Reminds me of: https://nautil.us/half-male-half-female-total-animal-234910/

Nature is real weird.

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