Ask HN: Non-spammy mass messaging on Twitter?

Well, it's about that time – time to get involved with Twitter. Yeah, I'm a little late to the party, but I think I've got some good ideas on how I can use Twitter to augment my business.

Ideally, I'd like to be able to send out mass semi-customized messages. I realize this is something Twitter probably doesn't want you to do, which is why you have to have followers to send out direct messages.

Now, I have heard you can use @reply to send messages to people who aren't following you. But then, don't all those @replies show up in your feed?

So if someone was to visit your profile, they'd see a bunch of @replies addressed to different people?

I want to do this in the most natural way possible. I figure there's gotta be a way to get in contact with a large amount of people, but thus far, I haven't found a method that shows real promise.

Is there any method you guys have found useful for contacting a lot of people through Twitter? Thanks!