Largest study of 3rd dose of Covid vaccine effectiveness shows Delta resistance

https://medicalxpress.com/news/2021-10-largest-real-world-dose-covid-vaccine.html

by pseudolus • 5 years ago

9 12 5 years ago

sp332• 5 years ago

The results show that, compared with individuals who received only two doses five months prior, individuals who received three doses of the vaccine (7 days or more after the third dose) had 93% lower risk of COVID-19-related hospitalization, 92% lower risk of severe COVID-19 disease, and 81% lower risk of COVID-19-related death. Vaccine effectiveness was found to be similar for different sexes, age groups (ages 40-69 and 70+) and number of comorbidities.

What does the headline mean then?

karmajunkie3• 5 years ago

i had the same question. i think it’s an unfortunate and confusing choice of words, where ‘delta resistance’ means resistance to delta (i.e. hospitalization, etc) rather than delta being resistant to the vaccine.

it’s a curious mistake to make in a medical outlet given the obvious implications of the word in context.

FjolsvithAase2• 5 years ago

More studies on Covid vaccines to consider:

https://brownstone.org/articles/22-studies-and-reports-that-...

karmajunkie3• 5 years ago

This is an obvious sham “institute”.

wingineer• 5 years ago

Under what criteria?

loceng2• 5 years ago

Does anyone know if it's standard or best practice for them to know who involved in these studies if they also have had COVID in the past?

I'm curious how much of the benefit may be from the vaccines vs. how much may be from catching COVID/have antibodies from COVID itself.

If they're not measuring this to differentiate, then why not?

n8henrie2• 5 years ago

Yes they do a pretty good job here, at least in my limited experience.

My wife and I are in the Pfizer study. We had a questionnaire, a swab, and blood draws for antibody levels on enrolling, and have had multiple sets of bloodwork since then to watch our response. We have a weekly symptom check-in, and for any suspicious symptoms are directed to get a COVID test and notify them so they can follow up on results. In case we are unable to go get a test, we were all provided with a test kit for home use (which gets sent back to them).

loceng2• 5 years ago

"... and for any suspicious symptoms are directed to get a COVID test and notify them so they can follow up on results"

So the answer is no then, they're not testing 100% of people. I don't know why you'd equate this as "a pretty good job" - it's not scientifically rigorous at all; much like how myocarditis signal in young men/boys only showed up between 1:3000 and 1:5000 but the most recent studies of even younger children only included 2000 participants, only 1200 of which receive the vaccine - so nowhere near enough participants included to catch important signals; and that's just for the "adverse" event of myocarditis.

And testing for antibodies produced by the vaccines and/or by natural COVID infection? I'd presume there's be a way antibody markers that can be checked for both - but something I'm also unsure of.

lern_too_spel• 5 years ago

It's a randomized trial. People in the trial having natural immunity would reduce the measured treatment effect, not increase it.

Largest study of 3rd dose of Covid vaccine effectiveness shows Delta resistance

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