Use of nanoparticles for detection of vascular calcification in atherosclerosis

https://pubs.rsc.org/en/content/articlelanding/2019/TB/C9TB01918A#!divAbstract

by bookofjoe • 7 years ago

36 21 7 years ago

pubs.rsc.org

LinuxBender6• 7 years ago

Would this complement a CAC test?

01100011• 7 years ago

Assuming they find calcified plaques, then what? Can they be reversed once they're calcified?

copperx• 7 years ago

No, as far as I know. But you can't improve what you can't measure.

throwawaymanbot2• 7 years ago

No they cant. But detection is paramount. CT Scans are costly and time consuming.

LinuxBender6• 7 years ago

Yes, some people keep magnesium, K2 MK-7, K2 MK-4 and D3 in their system to slowly break it down. This is done primarily to reverse the calcification in and around the heart to get a lower CAC score. Ideal score is 0.

throwawaymanbot2• 7 years ago

is there any proof "magnesium, K2 MK-7, K2 MK-4 and D3" works for this?

bigmit372• 7 years ago

Does this really work? First time I am hearing of this(would be estatic if it did).

Tharkun• 7 years ago

What is the clinical significance of the plaque being calcified? Is that worse (or better?) than "regular" cholesterol plaque? Or is that just another term for the same thing?

maerF0x0• 7 years ago

Not a doctor, but my understanding is that the calcification is a later stage of damage. Basically you get Inflammation, Plaques, Calcification in that order.

Someone more educated should chime in, or that could serve as a basis for starting your own learning

agumonkey• 7 years ago

Wild guess, it's a less flexible tissue state and may be near rupture.

From what I recall calcified arteries don't absorb blood waves and can transmit pressure downstream to fragile cells.

vo2maxer2• 7 years ago

The significance of obtaining a more accurate calcium score is in the stratification of cardiovascular and cerebrovascular disease. The calcium score has been correlated with higher risk for myocardial infarctions and strokes, but is just one of many factors guiding prevention. In the case where a patient has other concomitant risks such as hypertension and dyslipidemia, the clinician may advice more aggressive management. An example: https://www.medscape.com/viewarticle/915230

Use of nanoparticles for detection of vascular calcification in atherosclerosis

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