Human Connectome Project

http://www.humanconnectomeproject.org/

by jimsojim • 11 years ago

36 8 11 years ago

nulltype2• 11 years ago

What level of detail is available from this data?

The resolution is some of the best in the business, so to speak, but the biological interpretation of all MRI-derived metrics are still hotly debated. So the true level is detail is sort of dependent on something we don't know yet.

nulltype2• 11 years ago

Hmm, is there something like this where they just slice a brain directly rather than using low resolution MRIs?

Edit: oh here's one http://io9.com/see-the-first-ultra-high-resolution-3d-scan-o...

fintler• 11 years ago

http://www.humanconnectomeproject.org/data/inventory/

If I'm reading it correctly, it looks like either 1.5mm, 2mm, or 2.5mm, depending on the dataset.

apl• 11 years ago

The key bottleneck with all connectome projects is still reconstruction. There's on the order of a hundred billion neurones in the human brain; they're connected via 1,000-10,000 times the number of synapses. Current machine learning approaches are decent, but still require massive amounts of proof-reading.

Circuit neuroscience in Drosophila or the mammalian retina suggests neurones and synapses are indeed the level of detail we'll need in order to gain insight into computational mechanisms. So we're a long, long way off -- don't be too impressed by this particular dataset (which is insanely coarse!).

SapphireSun• 11 years ago

Hey if you guys want to help out with the proof reading effort, we've got a cool dataset that has a resolution of 16.5 nm x 16.5 nm x 23 nm at http://eyewire.org ^_^

fyrabanks• 11 years ago

This project and particular site have been around, largely unchanged, for many years.

The WU-Minn side of the project is seemingly more active, and their dataset is much, much easier to obtain: http://humanconnectome.org/data/. Their scripts for processing the data are up on github at https://github.com/Washington-University/Pipelines.

Human Connectome Project

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