Ask HN: Extramarket job hunting

I'm a web engineer who has spent some time (5 years total) working in DC and NYC, but is currently in KY because of multiple family health issues that have now played out.

I've noticed, spanning several years, that when I'm in a major market and put my resume out, I get lots of very serious attention (and some offers). When I'm out of such markets, I get some attention... but it always seems to peter out. It's as if my "score" as a candidate, however you want to define it, is weighted with a hefty discount.

But the reality is that aside from my family, I have zero attachment to this city. I am not married, don't have kids, have no significant friendships here, and my rent is negligible. Getting to NYC, or SF or ATL or wherever is literally a matter of packing a suitcase and getting on a plane.

How can I convince potential employers that I'm not a "relocation risk" or whatever it is they're thinking? What is my best course of action, aside from just picking up and moving to a larger market?